Steyaertlab

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België
Brussel
Steyaertlab

The daily live at the Steyaerlab

Nanobody-enabled structural biology: By rigidifying flexible regions and obscuring aggregative surfaces, nanobody complexes warrant conformationally uniform samples that are key to protein structure determination by X-ray crystallography. The elucidation of the first GPCR structure in its active state using a conformationally selective Nanobody demonstrates the power of the Nanobody platform to ge

nerate diffracting quality crystals of the most challenging targets including membrane proteins, flexible proteins, aggregating proteins and protein-protein complexes.

25/07/2024

Looking for a new challenging job? See https://jobso.id/jaaf

24/07/2024

Read our latest publication!

Protein-protein interactions are central in cell metabolism but research tools for their characterization are missing. Here, the authors introduce strategies for the discovery of nanobodies that modulate the SOS1•RAS complex formation.

19/06/2024

So proud to lead this team. Top talents, 16 nationalities, world class science and game changing discoveries. A fruitful cocktail that we translate into value for society!

13/03/2024

With the support of VIB and VUB, our lab is building a brand new bio-incubator Brussels on campus Etterbeek. Looking for space for your biotech start-up? You can check in before the end of this year!

18/12/2022

Congratulations to Alexandre WOHLKÖNIG and Valentina KALICHUK for obtaining a VLAIO innovation grant!

18/12/2022

We thank the FWO for financing 'Nanobodies4INSTRUCT 3.0’. In 2014, we founded Nanobodies4Instruct as part of Instruct-ERIC, one of the first ESFRI projects that provides cutting-edge technology, scientific expertise and pioneering training. Any scientist from an Instruct member state can submit a proposal for access to the Nanobodies4Instruct center for the generation of conformational Nbs and now also megabodies to facilitate the structural analysis of proteins that are notoriously difficult to purify, crystallize or study by any other method.

12/05/2022

A milestone for our team. Our 20th contribution to Nature was published on line last night!

Structural studies of human Na+–taurocholate co-transporting polypeptide in complex with nanobodies reveal mechanisms for bile salts transport and HBV recognition involving an open-pore intermediate state.

30/06/2020

Tomasz just finished his PhD in our lab! We wish him a great future!

23/01/2019

Another contribution from our lab to top science .

Article

23/01/2019

Description VIBis a more than1500 scientists counting life science research institute in Flanders, Belgium. VIB has a long-standing history of translating scientific breakthroughs into impact

23/09/2018

How we built a cryo-EM center in 7 minutes

23/05/2018

Group Leader and Junior Group Leader Positions in Structural, Molecular and Cellular Biology - VIB are looking for a Other in Brussels, Belgium. Salary: unspecified, Hours: , Type:

Adres

Vrije Universiteit Brussel
Brussel
1050BRUSSEL

Website

http://steyaertlab.eu/

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