TargetingOne Technology Corporation-Beijing

27/10/2023

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Through continued innovation to meet market demand, becoming a China-based leading IVD company on the world stage.For more information, please contact info...

29/07/2022

World Hepatitis Day is marked on 28 July each year to increase the awareness and understanding of viral hepatitis.
TargetingOne HBV DNA assay uses microdroplet digital PCR for the absolute quantification of HBV DNA in serum or plasma samples, which increases the sensitivity of the assay and avoids PCR false negatives.

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28/07/2022

TargetingOne sincerely invites you to FIME 2022 from July 27th to 29th at Miami Beach Convention Center. Meet us at Booth C88.
TargetingOne is a high-tech and leading enterprise in China, especially specialized in molecular diagnosis. Product lines cover Immuno-POC, Sampling, Extraction and Real-time PCR. We have more than 120 species products and most of them aquired CE, FSC, NMPA, CE-Chamber of Commerce White List. We have applied for more than 170 domestic and foreign patents and more than 90 patents granted.

22/07/2022

A ddPCR assay for ctDNA EGFR mutation detection in NSCLC patient was established by Chuanhao Tang, Lingxiang Zhu, Lijuan Zhang, Chianru Tan, Zhiyong Peng, Baoxia Liu, Wenjing Liu, Haixu Hu, Yu Bai, Bo Wang, Li Lin, Jun Liang, Xiaoyan Li, Yong Guo, Yi Liu.
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http://www.targetingone.com/en/Publications/info.aspx?itemid=348
https://doi.org/10.1016/j.cca.2020.07.003

20/07/2022

Nucleic acid extraction is the first step of any amplification experiment no matter what kind of amplification is used to detect a specific pathogen. It is a crucial preanalytic step in the development and performance of any successful molecular diagnostic method and ensures a reliable result. We must pay attention to the technical progress of the nucleic acid extraction as well as to the method for amplification and detection of nucleic acids in order to obtain satisfactory results. Nucleic acid extraction consists of three major processes: isolation, purification, and concentration.

http://www.targetingone.com/en/NewYiDynamics/info.aspx?itemid=512

15/07/2022

The spinal muscular atrophy (SMA) digital PCR detection kit is designed based on droplet digital PCR technology for the detection of the copy number variation in exons 7 and 8 of the SMN1 gene and exons 7 and 8 of the SMN2 gene in genomic DNA. In droplet digital PCR, tens of thousands water-in-oil nanoemulsions can be generated using microfluidic chip, the ratio of the DNA copies of target and reference genes can be used to interpret dPCR results.

Related Product: http://www.targetingone.com/en/product/info.aspx?itemid=464&lcid=14&pid=
https://www.linkedin.com/feed/update/urn:li:ugcPost:6953636380740661248?updateEntityUrn=urn%3Ali%3Afs_updateV2%3A%28urn%3Ali%3AugcPost%3A6953636380740661248%2CFEED_DETAIL%2CEMPTY%2CDEFAULT%2Cfalse%29

12/07/2022

(FIATA)-based reverse transcription droplet digital PCR (RT-ddPCR) was developed and performed for ALK status survey in NSCLC samples. An absolute quantitative FIATA-based RT-ddPCR was developed and validated for ALK fusion detection in NSCLC. This method can rapidly, accurately, and objectively classify ALK types and help with individual therapy.
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http://www.targetingone.com/en/Publications/info.aspx?itemid=347
https://doi.org/10.1111/1759-7714.13535

08/07/2022

The “sample-to-answer” integration and automation of circulating tumor DNA (ctDNA)-based liquid biopsy using digital PCR(dPCR) has been hampered by the complicated operations of liquids with volumes ranging from milliliter samples to nanoliter droplets. On the basis of a “3D extensible” design paradigm proposed previously, an integrated droplet digital PCR (IddPCR) microdevice was successfully developed to automate the entire process of liquid biopsy. This work offers a feasible solution for the automation of liquid biopsy and paves the way for its broad applications in clinics.



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http://www.targetingone.com/en/Publications/info.aspx?itemid=346
https://pubs.acs.org/10.1021/acs.analchem.0c00818

05/07/2022

A study show the identification of atypical and cryptic ALK rearrangements using an optimal algorithm. ALK status was analyzed using a Human ALK Gene Fusion Detection Kit with the primers covering nucleotide, respectively (TargetingOne, Beijing, China). In this study, it was not only useful for the detection of IHC, FISH, and NGS false-negative specimens, but also indicated the possibility of atypical ALK aberration.

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https://doi.org/10.1007/s00432-020-03166-1
http://www.targetingone.com/en/Publications/info.aspx?itemid=345

01/07/2022

Take Action to Prevent Flu. Acoording to CDC, this season, all flu vaccines will be designed to protect against the four flu viruses that research indicates will be most common. TargetingOne has developed several influenza diagnostic detection kits to help prevent and control influenza.

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https://www.linkedin.com/pulse/influenza-rise-targetingone-help-prevent-

28/06/2022

Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disease characterized by the degeneration of motor neurons and progressive muscle atrophy. Here, we developed a single-tube multiplex digital polymerase chain reaction (dPCR) assay for simultaneous determination of the copy numbers of SMN1 and SMN2.

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https://pubs.acs.org/doi/pdf/10.1021/acs.analchem.1c04403 #

24/06/2022

The covalently closed circular DNA (cccDNA) library formed in the liver is the main reason why hepatitis B virus (HBV) is not completely cleared and persistently infected. Recently, Professor Ren Feng's research team from Beijing Youan Hospital, Capital Medical University. Beijing. China published a paper in the international journal Hepatology International (2021 IF=8.586) entitled "CRISPR/Cas13-assisted Hepatitis B Virus Covalently Closed Circular DNA Detection", using the digital PCR product from TargetingOne as a reference standard for assay sensitivity and positive detection rate, which can also test the effectiveness of sample pre-treatment.
TagretingOne looks forward to more adoption of digital PCR technology used in scientific research.



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https://doi.org/10.1007/s12072-022-10311-0
http://www.targetingone.com/en/Publications/info.aspx?itemid=454