Dalian Handom Chemicals Co.,Ltd.

05/10/2025

Hello everybody,

Recently, a troll (u/Worldly_Falcon598) on Reddit has been deliberately smearing our company and misleading public opinion, he/she fabricated a story about purchasing products from our company in August and claimed that we refused to ship or issue refunds, this behavior has severely damaged our company's reputation. Since users on Reddit are all fictitious names, their real names can not be verified, making it difficult for us to defend our rights.

Another account (u/Free-Contribution894) is impersonating our export director who is called John Wang.

All new and existing customers who have any inquiries, please contact us through the email addresses on our official websites. Our three official websites are:

www.handom-chem.com
www.handomchemical.com
www.handomchemicals.com

You can also contact us via WhatsApp, WhatsApp numbers are:
+86 15840669648
+86 15998584536

Other methods are not official contact information, so please be cautious.

If you find anyone else spreading malicious rumors, please feel free to let us know, thank you!

DALIAN HANDOM CHEMICALS CO.,LTD.

Dalian Handom Chemicals Co.,Ltd is a 10-year-experienced supplier of Organic Chemicals from northeast of China, which includes APIs & Pharmaceutical

06/04/2025

Product Name: Retatrutide Lyophilized Powder
CAS No.: 2381089-83-2
Molecular Formula: C221H342N46O68
Molecular Weight: 4730.91
Purity: ≥99.0%
Dosages: 5mg/Vial, 10mg/Vial, 15mg/Vial, 20mg/Vial, 30mg/Vial or customized.

Brief Introduction:
Retatrutide is an active compound released by Eli Lilly in June 2023. It is a triple (GLP-1/GIP/Gcg) agonist based on the GLP/GI dual receptor agonist Tirzepatide through a hybrid glucagon (GlucagonGcg) related structure, and is a drug for the treatment of obesity and type 2 diabetes. This active compound can activate receptor agonists in our body, which helps control blood sugar and weight loss management.

Sequence:
H-Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-α-Me-Leu-Leu-Asp-Lys-{diacid-C20-gamma-Glu-(AEEA)-Lys}-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2

Mechanism of Action:
Retatrutide achieves comprehensive metabolic regulation through triple receptor activation:
※ GLP-1R: Slows gastric emptying, enhances satiety, and reduces appetite.
※ GIPR: Regulates hunger signals in the central nervous system, further suppresses appetite and improves energy metabolism.
※ GCGR: Promotes glucagon secretion, accelerates fat and glycogenolysis, and increases basal metabolic rate.

Indications and Efficacy:
★ Obesity Treatment:
In the Phase II clinical trial, patients in the highest dose group (12 mg) lost an average of 24.2% weight after 48 weeks, and some patients lost more than 30%.
★ Metabolic Dysfunction-Associated Fatty Liver Disease (MASLD):
Retatrutide can reduce liver fat content by 86%, and more than 85% of patients achieve regression of liver steatosis.

★ Type 2 Diabetes:
Significantly reduce glycated hemoglobin (HbA1c) and improve blood sugar control.

★ Potential Cardiovascular Benefits:
Animal studies have shown that it may indirectly protect cardiovascular health by improving blood pressure and heart function, but further clinical verification is needed.

Packaging:
① 5mg/vial, 10 vials packed in one box.
② 10mg/vial, 10 vials packed in one box.
③ 15mg/vial, 10 vials packed in one box.
④ 20mg/vial, 10 vials packed in one box.
⑤ 30mg/vial, 10 vials packed in one box.

Storage Conditions:
Preserved in air tight containers, protected from light.
(Recommended temperature: -25℃ ~ -15℃)

Shelf Life:
24 months from the date of manufacturing when stored under the above conditions.

27/02/2025

Tirzepatide is the world's first and currently the only glucose-dependent insulinotropic polypeptide (GIP)/glucagon-like peptide-1 (GLP-1) receptor agonist. Developed by Eli Lilly, it was approved for marketing in China on May 21st, 2024, and officially launched on January 2nd, 2025. It is suitable for adult patients with type Ⅱ diabetes whose blood sugar is still poorly controlled by metformin and/or sulfonylurea drugs on the basis of diet control and exercise.

22/02/2025

A 40-foot container of soybean lecithin powder is being loaded and prepared to be delivered to Qingdao Seaport.

Brief Introduction:
Soybean lecithin powder, also called soya lecithin powder or soy lecithin powder, which is a mixture of phospholipids extracted from soybean oil, mainly composed of ingredients such as phosphatidylcholine, phosphatidylethanolamine and phosphatidylinositol. It is usually light yellow to brown and has emulsifying, stabilizing and antioxidant properties.

Main Ingredients:
1) Phosphatidylcholine (PC): Helps cell membrane structure and function.
2) Phosphatidylethanolamine (PE): Participates in cell signaling.
3) Phosphatidylinositol (PI): Plays an important role in cell signaling and membrane structure.

Product Features:
1) This product has high purity and good fluidity, and the powder can pass 60 mesh.
2) Soya lecithin powder has high PC content and low peroxide value, and can be used as a raw material for producing high-purity PC and PS.
3) Soy lecithin powder is a de-oiled and refined powdered phospholipid product. The HLB value is about 7, easily dispersed in water, soluble in oil and fat, and partially soluble in ethanol.

Application & Functions:
① Pharmaceutical products: Used in liposomes or drug embedding emulsifiers, raw materials and auxiliary materials for drugs for the treatment of fatty liver, hyperlipidemia, etc.
② Raw materials for the production of PC and PS: Promote cell regeneration, improve brain function and intelligence.
③ Health products, milk powder, soy protein, solid beverages: Brain-nourishing, liver-protecting, blood lipid-lowering, nutritional supplementation, improving product dispersion and solubility, and improving stability.
④ Bread, cakes, biscuits and other baked goods: It helps to disperse oil, increase food elasticity, make it softer, reduce viscosity, prevent aging, and improve foaming properties.
⑤ Instant noodles, noodles, crisp noodles, popcorn, potato chips: Make noodles moist, soft and elastic, reduce starch dissolution during boiling, reduce viscosity, facilitate processing, and increase crispness.
⑥ Chocolate, candy, chewing gum: Reduce viscosity, facilitate film removal, improve flexibility and chewing taste, and prevent sticking to teeth.
⑦ Meat products: Improve the combination of protein, starch and water, and improve the water retention and moisture retention of meat products.
⑧ Lecithin soft capsules, hard capsules: Brain-boosting, intelligence-enhancing, cell growth-promoting, blood lipid-regulating, liver-protecting.
⑨ Margarine, jam, shortening: Emulsifiers and anti-splashing agents.
⑩ Pet food, eel feed and other high-end feed: Improve animal hair, reduce hair loss, increase gloss, promote fish fry growth, increase survival rate, and provide necessary nutrition.