International Institute of Molecular and Cell Biology in Warsaw

International Institute of Molecular and Cell Biology in Warsaw We support ambitious scientists of any nationality, driven by passion to pursue frontier research. Privacy policy: https://www.iimcb.gov.pl/en/privacy-policy
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04/08/2026

🖥️ The Mass Spectrometry Facility supports researchers in translating complex biological samples into high-quality molecular data.

🧫 The facility provides bottom-up proteomics, interactomics, consultations, data analysis and custom method development. Its advanced instrumentation enables high-resolution analysis of proteins and other biomolecules, supports studies based on limited sample material, and helps generate actionable insights for biomedical research.

🤝 From experimental design to data acquisition and interpretation, the team works with researchers to build workflows adapted to the scientific question.

Learn more on the main IN-MOL-CELL website: https://inmolcell.iimcb.gov.pl/

IN-MOL-CELL Infrastructure is funded by the European Union - NextGenerationEU under the National Recovery and Resilience Plan. IN-MOL-CELL Infrastructure is also funded by the European Union under Horizon Europe, Project 101059801 - RACE, and by the RACE-PRIME project carried out within the IRAP programme of the Foundation for Polish Science, co-financed by the European Union under the European Funds for Smart Economy 2021-2027.

Behind the Institute’s research and daily operations, the Public Procurement Unit led by Jakub Wielgus ensures that good...
03/08/2026

Behind the Institute’s research and daily operations, the Public Procurement Unit led by Jakub Wielgus ensures that goods, services, and construction works are delivered on time and in compliance with procurement requirements. ⏰

The Unit combines procurement expertise with close cooperation with researchers and administrative teams, providing practical guidance, preparing documentation, and supporting responses to audits and grant-related requirements.

This helps streamline internal processes, reduce the administrative burden on project teams, and contribute to financial discipline. ⚙️

30/07/2026

Iron is essential for numerous biological processes, including oxygen transport, DNA synthesis, and cellular respiration.

At the same time, maintaining a tightly regulated iron balance is crucial, as both iron deficiency and iron overload can lead to severe health issues. ⚖️

The Laboratory of Iron Homeostasis, led by Katarzyna Mleczko-Sanecka, PhD, aims to elucidate the mechanisms regulating iron across tissues and cell types. Its research focuses on iron recycling from erythrocytes and the systemic sensing of the body’s iron burden.

Learn more about the Lab’s research, future goals, and team in the latest Inside IIMCB carousel ⬇️

28/07/2026

🐟Some of the biggest biological questions can be studied in a small vertebrate model. At the Zebrafish Core Facility, the IN-MOL-CELL infrastructure at the International Institute of Molecular and Cell Biology in Warsaw supports life science research using Danio rerio as a model organism.

🐠The facility provides high-quality zebrafish lines, controlled aquatic systems, specialized equipment and technical expertise for studies in developmental biology, genetics, neurobiology and biomedical research.

🔬Its services include breeding and maintaining zebrafish lines, providing embryos and adult fish for experiments, microinjection of zebrafish embryos, screening embryos for fluorescence signals, cryopreservation of zebrafish s***m, tissue sampling, genotyping, and fish handling and welfare training for new and experienced users.

🦠Researchers receive support from early experimental planning to project ex*****on. The team also collaborates with research groups in Poland and abroad, sharing expertise in zebrafish breeding, care and aquatic system management, and exchanging zebrafish lines with other research centers. Explore what zebrafish can bring to your research.

Learn more on the main IN-MOL-CELL website: https://inmolcell.iimcb.gov.pl/

IN-MOL-CELL Infrastructure is funded by the European Union - NextGenerationEU under the National Recovery and Resilience Plan. IN-MOL-CELL Infrastructure is also funded by the European Union under Horizon Europe, Project 101059801 - RACE, and by the RACE-PRIME project carried out within the IRAP programme of the Foundation for Polish Science, co-financed by the European Union under the European Funds for Smart Economy 2021-2027.

Often working behind the scenes, Laboratory Support Specialists at IIMCB, coordinated by Paula Kwapisz, serve as the Ins...
27/07/2026

Often working behind the scenes, Laboratory Support Specialists at IIMCB, coordinated by Paula Kwapisz, serve as the Institute’s “circulatory system” - essential to the smooth and efficient operation of every laboratory. 👩‍💻

They coordinate ordering processes, laboratory supplies, communication flow, and day-to-day logistics, ensuring that research activities run smoothly and efficiently. The LSS’ responsibilities are diverse and tailored to the specific needs of each lab, which reflects the dynamic nature of the Institute.

As IIMCB continues to grow, the LSS team’s role is becoming increasingly visible - while remaining essential to the success of every laboratory.

🔬 RNA is one of biology’s most versatile molecules. It carries genetic information, helps regulate gene expression and t...
24/07/2026

🔬 RNA is one of biology’s most versatile molecules. It carries genetic information, helps regulate gene expression and takes part in key cellular processes. This makes RNA an attractive target for drug discovery. Yet researchers still lack robust computational tools to predict how small molecules bind to RNA.

☝ Filip Stefaniak, PhD, DSc Habil, from the Laboratory of Bioinformatics and Protein Engineering at theIIMCB, aims to address this gap. His new NCN-funded project will develop DeepLeaRNA, a computational tool for predicting and explaining RNA–ligand binding.

🧪 Small-molecule ligands can bind RNA and modulate its structure and function, making RNA-ligand interactions a promising but underexploited target class in drug discovery. Understanding how and why a given ligand binds a specific RNA — its binding mode, pocket, and the structural determinants that govern it — is a critical early step in evaluating and designing compounds with potential biomedical or therapeutic relevance. “DeepLeaRNA will use advanced machine learning techniques and a and multiple molecular modeling methods to achieve accuracy and interpretability. It will provide insight into the molecular recognition process,” says Filip Stefaniak.

🦠The project will focus not only on prediction, but also on explanation. This matters because researchers need to know more than whether a molecule may bind to RNA. They also need to understand why such binding is likely and which molecular features shape the interaction.

🦾 The project “Data-driven Methodology for Predicting, Explaining, and Understanding of RNA and Small Molecule Ligand Binding” received 1,458,376 PLN in funding under the OPUS 30 call.

Funding note
The project described in this article is funded by the National Science Centre, Poland: “Data-driven Methodology for Predicting, Explaining, and Understanding of RNA and Small Molecule Ligand Binding”, project no. 2025/59/B/NZ2/01768, OPUS 30.

23/07/2026

Science should not stay behind laboratory doors. It matters most when it reaches people - when it becomes accessible, understandable, and connected to everyday life. 🌍💡

For over two decades, BioCentrum Edukacji Naukowej has served as a bridge between research and education. Since 2015, IIMCB has been BioCEN’s strategic sponsor.

BioCEN popularizes modern experimental natural sciences through hands-on educational activities for primary and high school students across Poland. Its workshops cover areas such as molecular and cell biology, immunology, biochemistry, microbiology, biophysics, environmental sciences, medical sciences, and more — always with a strong focus on practical and experimental approaches.

BioCEN also supports young science enthusiasts, biology teachers, scholarship recipients of the National Children’s Fund, and students visiting IIMCB for lectures, interactive activities, and guided tours of research facilities.

BioCEN’s mission is supported by its partners: the Nencki Institute, the Institute of Biochemistry and Biophysics PAS, the Faculty of Biology of the University of Warsaw, the Polish Academy of Sciences, and the Zuzanna Ginczanka High School in Warsaw.

🧬 DNA and RNA rarely work alone. In living cells, they often team up with proteins to form complexes that help control g...
22/07/2026

🧬 DNA and RNA rarely work alone. In living cells, they often team up with proteins to form complexes that help control gene expression, antiviral defence and development. These complexes are central to biology, but they remain hard targets for drug discovery.

🖥️ Grigory Nikolaev, PhD, from the Laboratory of Bioinformatics and Protein Engineering at the International Institute of Molecular and Cell Biology in Warsaw, will tackle this problem with DeepGeNAPL. His new NCN-funded project will develop an AI tool to study and generate small molecules that target nucleic acid–protein complexes.

🧩 The project focuses on DNA–protein and RNA–protein assemblies. These systems matter because they regulate many cellular processes. Yet researchers still lack effective ways to design small molecules that engage them predictably.

💬 “The system will support two linked tasks. First, it will help researchers analyse how small molecules interact with DNA-protein and RNA-protein assemblies. Then it will use that information to guide the design of new molecular candidates. This should make the early search for biologically active compounds more focused, while keeping the claims at the level of discovery support rather than promising new drugs,” says Grigory Nikolaev.

☝ DeepGeNAPL will therefore support an early stage of discovery. It will help researchers explore hard molecular targets, understand possible interactions and select more promising molecular candidates for further study.

🦾 The project develops IIMCB expertise at the intersection of artificial intelligence, structural bioinformatics, nucleic acid biology and molecular medicine. It also supports a broader research direction: developing computational tools for biological targets that are important, but hard to study with standard methods.

📊 The project “Deep learning–driven design of small molecules targeting nucleic acid–protein complexes” received 687,092 PLN in funding under the 21 call.

Funding note:
The project described in this article is funded by the National Science Centre Narodowe Centrum Nauki, Poland: “Deep learning–driven design of small molecules targeting nucleic acid–protein complexes”, project no. 2025/59/D/ST6/02248, SONATA 21.

21/07/2026

🐁The Rodent Facility supports standardized, ethical and reproducible in vivo research with mouse models. Its work starts from a core principle: high standards of animal welfare are essential for high-quality science.

🧪 The facility maintains mice under specific pathogen-free conditions and supports breeding, cohort planning, controlled dietary interventions, metabolic and behavioral phenotyping, biochemical analysis, and consulting on projects involving mouse models.

🔬Advanced systems such as Digital Ventilated Cages enable continuous, non-invasive monitoring of animal activity and welfare, while specialized metabolic and behavioral platforms help characterize disease models and assess treatment effects.

Learn more on the main IN-MOL-CELL website: https://inmolcell.iimcb.gov.pl/

IN-MOL-CELL Infrastructure is funded by the European Union - NextGenerationEU under the National Recovery and Resilience Plan. IN-MOL-CELL Infrastructure is also funded by the European Union under Horizon Europe, Project 101059801 - RACE, and by the RACE-PRIME project carried out within the IRAP programme of the Foundation for Polish Science, co-financed by the European Union under the European Funds for Smart Economy 2021-2027.

Effective research governance helps science move forward responsibly and efficiently. 👌 The Scientific Coordination Unit...
20/07/2026

Effective research governance helps science move forward responsibly and efficiently. 👌

The Scientific Coordination Unit, headed by Iwona Pilecka, PhD, supports IIMCB’s research governance with a focus on open science, responsible animal research, and infrastructure support.

In 2024–2025, the SCU implemented new internal rules for open-access publishing, advised researchers on funders’ OA requirements, and streamlined documentation and reporting for laboratory animal studies. 🐭

The Unit also supported key institutional processes, including preparations for the evaluation of IIMCB’s scientific activity, curation of research outputs in the Polish Scientific Bibliography, and development of evidence-based societal and economic impact case descriptions.

In 2026, the SCU developed and launched the Scientific Outputs Collection, a centralized platform that integrates publications, preprints, awards, and grants of IIMCB.

The platform ➡️ https://lnkd.in/dg4mJtg7 offers advanced search and filtering options and improves visibility, accessibility, and management of the Institute’s research achievements.

Adres

Warsaw

Godziny Otwarcia

Poniedziałek 09:00 - 17:00
Wtorek 09:00 - 17:00
Środa 09:00 - 17:00
Czwartek 09:00 - 17:00
Piątek 09:00 - 17:00

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