Moseley Lab

29/03/2023

Very happy to share this one - starting to answer questions we started asking maybe 15 years ago about rabies virus P protein... best summarised as 'how do viral proteins do so much?"

Thanks to our our many long term collaborators and friends at .

Viruses form extensive interfaces with host proteins to modulate the biology of the infected cell, frequently via multifunctional viral proteins. T...

12/10/2022

https://journals.asm.org/doi/10.1128/jvi.01396-22 #.Y0cz7wES4oM.twitter

Lyssaviruses, including rabies virus, cause rabies, a progressive encephalomyelitis that is almost invariably fatal. There are no effective antivirals for symptomatic infection, and effective application of current vaccines is limited in areas of ...

16/05/2022

Pleased to share new one from collab. with Gifu uni and colleagues on how rabies disarms a pre-existing antiviral state... involving phosphoSTAT1 https://t.co/23zM5XPn6a
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1010533

“Pleased to share new one from collab. with Gifu uni and colleagues on how rabies disarms a pre-existing antiviral state... involving phosphoSTAT1 https://t.co/23zM5XPn6a”

18/12/2021

“New from , and co, used to reveal previously undetected (MT) damage caused by clinically relevant nanomolar doses of . https://t.co/pugqoWqeRs ”

18/12/2021

“In happy news: welcoming Alebachew Messele, and celebrating/farewelling Tianyue Zhao's on her move on to her next big career step in Sydney.”

17/12/2021

“ end of the year we never thought would end, much like the ARC - happy holidays everyone.”

16/12/2021

“Got a paper published in Sweet!!😁It's a study to characterize drug-induced dysfunction. Many thanks to 🙏 Check it out: https://t.co/Oc7NK1HugR”

16/12/2021

“Congratulations to Tianyue Zhao, now a Dr. and winner of the CSL PhD prize in Microbiology...!”

08/10/2021

Very pleased to share new paper on rabies P protein with Aaron Brice and colleagues
https://t.co/5V83Iy5Pkz

The P3 protein of the pathogenic rabies virus strain Nishigahara undergoes nuclear trafficking via several nuclear localization and nuclear export sequences, which results in accumulation of P3 in th...

17/09/2021

Why viral infections are so hard to cure, and how antivirals like COVID-19 drug remdesivir workABC Science / By science reporter Belinda Smith for Science FrictionPosted Sat 11 Sep 2021 at 7:00pmSaturday 11 Sep 2021 at 7:00pm, updated Sun 12 Sep 2021 at 12:37amSunday 12 Sep 2021 at 12:37am Cold sore...