sQube Colloidal AFM Probes

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sQube Colloidal AFM Probes sQube® is the world leading manufacturer of colloidal probes for Atomic Force Microscopy (AFM)

sQube® is the world-wide market leading manufacturer of Colloidal AFM Probes. Colloidal probes are AFM probes with а spherical colloidal particle attached to the free end of the AFM cantilever by a suitable adhesive. They are commonly used for force measurements on different samples in air and liquids.

Check out this report by Bril et al., which covers the use of UV microsculpting to pattern topography on mechanically co...
25/09/2026

Check out this report by Bril et al., which covers the use of UV microsculpting to pattern topography on mechanically compliant substrates for cell culture. Such substrates are important in investigating the effect cell-substrate interactions in health and disease. CP-qp-CONT-PM-C cantilevers were used to mechanically characterize the substrates.
Read it here📑- https://www.cell.com/cell-reports-physical-science/fulltext/S2666-3864(26)00121-9
Shop here 🔺🛒 - https://www.sqube.com/Colloidal-AFM-Probe-CP-qp-CONT-PM

What’s in a name? That which we call a CP-NCH-SiO-C by any other name would indent just as reliably, accurately and affo...
13/08/2026

What’s in a name? That which we call a CP-NCH-SiO-C by any other name would indent just as reliably, accurately and affordably.
While the paraphrase above is absolutely true, it is important to refer to AFM probes used in a methods section correctly. This helps other researchers (and especially AFM newcomers) reproduce your work and compare results!

Using chemically crosslinked bovine-serum albumin (BSA) networks as a model system, Becker et al. show that the same hyd...
16/03/2026

Using chemically crosslinked bovine-serum albumin (BSA) networks as a model system, Becker et al. show that the same hydrogel can dissipate stress through two distinct regimes depending on protein conformation. Native BSA hydrogels exhibit viscoelastic relaxation, governed by unfolding of protein domains, whereas chemically denatured BSA hydrogels display poroelastic dissipation, dominated by solvent migration through the deformed matrix.
A wide variety of materials were tested in the study, both as experiments as controls. CP-NCH-SiO-D was used for PDMS elastomer samples, while the softer CP-CONT-SiO-D and CP-CONT-SiO-E were used for the softer hydrogels of PAAm and BSA under different conditions.
Read full article here: https://www.sciencedirect.com/science/article/pii/S1742706126001224

Looking to perform colloidal probe experiments on very soft samples in liquid? Check out our CP-qp-SCONT series of produ...
02/02/2026

Looking to perform colloidal probe experiments on very soft samples in liquid? Check out our CP-qp-SCONT series of products. They are made of a quartz-like material and have a rectangular shape, with a nominal force constant of 0,01 N/m. A partial reflective gold coating is deposited on the free end of the detector side of the AFM cantilever. The main advantages of the coating are the low bending and the reduced drift, particularly for measurements in liquid environments.

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