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Sernova Sernova is a clinical-stage regenerative medicine theraupeutics company

Sernova is a clinical-stage biotechnology company that is advancing its implantable Cell Pouch™ bio-hybrid organ which works to restore the body’s normal function so that people with type 1 diabetes (T1D) and other chronic diseases can focus on what matters most: living their lives.

10/19/2026

Patricia Beaston, MD, PhD, has joined Seraxis as Chief Medical Officer.

Upon completion of our proposed merger with Seraxis, she will become Chief Medical Officer of the combined company, BetaNova Biotherapeutics.

Dr. Beaston has 24 years of FDA leadership experience. She served across three of the FDA’s principal centers: Center for Drug Evaluation and Research (CDER), where she evaluated endocrine therapeutics; Center for Devices and Radiological Health (CDRH); and most recently Center for Biologics Evaluation and Research (CBER), where her review responsibilities included islet cell transplantation, immune modulation in type 1 diabetes (T1D), and cell and gene therapies.

Her expertise will strengthen clinical and regulatory leadership for BetaNova as SR-02, investigational pancreatic stem cell-derived insulin-producing islets, are advanced into a Phase 1/2 clinical trial. The first patient dosing for the trial is targeted for Q1 2027.

Together, Sernova and Seraxis will aim to bring together complementary science, technology, and expertise to advance new treatment options for people living with T1D.

Read the full announcement for more details: https://sernova.com/press_releases/seraxis-and-sernova-announce-appointment-of-former-fda-medical-officer-dr-patricia-beaston-as-chief-medical-officer-of-seraxis-and-post-merger-betanova-biotherapeutics/

Check out the most recent episode of Cell & Gene: The Podcast featuring our President and CEO, Jonathan Rigby, and Serax...
10/13/2026

Check out the most recent episode of Cell & Gene: The Podcast featuring our President and CEO, Jonathan Rigby, and Seraxis President and CEO, Will Rust, PhD. With host Erin Harris, they discuss what it will take to move closer to a functional cure for type 1 diabetes, and why Sernova and Seraxis have proposed a merger to form BetaNova Biotherapeutics.

The conversation covers why Sernova’s retrievable Cell Pouch in combination with Seraxis’ stem cell-derived islets is a natural fit, the challenge of manufacturing islet cells at scale, and our planned approach to reducing the need for immune suppression. Jonathan, who has lived with T1D since age 18, also shares why this mission is personal for our team.

Watch the full episode: https://bit.ly/4z5gLhP

Jonathan Rigby, President and CEO of Sernova, recently joined Ginger Vieira for an episode of the Diabetes Nerd Podcast....
10/08/2026

Jonathan Rigby, President and CEO of Sernova, recently joined Ginger Vieira for an episode of the Diabetes Nerd Podcast. Topics covered during their discussion include:

➡️ Why insulin, CGMs, and pumps address only part of what a healthy pancreas does

➡️ How the Sernova Cell Pouch is designed to naturally vascularize with surrounding tissues for the long-term survival and function of cells, with complete retrievability

➡️ What our planned merger with Seraxis could mean for manufacturing and supplying stem cell-derived pancreatic islet cells

➡️ How we’re approaching a reduction in immune suppression over time, including next-generation gene-edited cells

➡️ Jonathan’s lived experience with type 1 diabetes, which informs the urgency of our mission to advance a potential function cure

Watch the full conversation on YouTube: https://bit.ly/3Vysp5P

10/05/2026

In connection with the recently proposed merger of Sernova and Seraxis, a financing round of $11.2 million has been closed.

The funds will be used to support cGMP manufacturing of SR-02, Seraxis’ lead stem cell-derived pancreatic islet cell program, and first patient dosing of SR-02 in the Phase 1/2 trial in Q1 2027 under an FDA-cleared IND with initial clinical data anticipated in H1 2027.

Read more about the additional plans for the new funding in our press release: https://bit.ly/4hDZEgN

Join us today at 1:30 p.m. ET as we present at NOBLE Capital Markets’ Emerging Growth Virtual Equity Conference to highl...
10/01/2026

Join us today at 1:30 p.m. ET as we present at NOBLE Capital Markets’ Emerging Growth Virtual Equity Conference to highlight the details and strategy of our proposed merger agreement with Seraxis.

Jonathan Rigby, President and CEO of Sernova and William L. Rust, Ph.D., President and CEO of Seraxis will participate in a joint presentation and fireside-style Q&A. Together they will highlight the synergies of combining investigational technologies such as Sernova’s Cell Pouch Bio-hybrid Organ with Seraxis’ stem cell-derived pancreatic islet cell programs and in-house cGMP manufacturing capabilities in pursuit of a potential functional cure for ( ) islet cell replacement.

Tune in here: https://bit.ly/3TWDEo6

We’re excited about what our teams are building together and the potential of combining our technologies to help shape t...
09/25/2026

We’re excited about what our teams are building together and the potential of combining our technologies to help shape the future of cell replacement therapy.

Hear directly from Will Rust, PhD, CEO of Seraxis, as he joins Ginger Vieira on the Diabetes Nerd podcast to discuss SR-02 and SR-03, Seraxis’ investigational stem cell-derived pancreatic islet cell therapies, and the science behind their development to treat ( ).

Watch here: https://bit.ly/4yjbZga

Attending the 28th Annual HC Wainwright Global Investor Conference?  Join us as CEO of Sernova, Jonathan Rigby, and CEO ...
09/14/2026

Attending the 28th Annual HC Wainwright Global Investor Conference?

Join us as CEO of Sernova, Jonathan Rigby, and CEO of Seraxis, Will Rust, Ph.D., present details of our merger forming BetaNova Biotherapeutics to offer a differentiated approach to ( ) islet cell replacement therapy.

Read more in our press release: https://bit.ly/3T3Y2mH

Don’t forget to join us tomorrow, September 11, at 10 a.m. EDT, as we host a virtual investor webinar to highlight the d...
09/10/2026

Don’t forget to join us tomorrow, September 11, at 10 a.m. EDT, as we host a virtual investor webinar to highlight the details of our definitive merger agreement with SeraXis.

The webinar will feature Jonathan Rigby, President and CEO of Sernova and proposed CEO of the combined company, and William L. Rust, Ph.D., President and CEO of Seraxis and proposed President and Chief Scientific Officer of the combined company. They will provide an overview our plans to combine Sernova’s Cell Pouch Bio-hybrid Organ with Seraxis’ stem cell-derived pancreatic islet cells to create a clinical-stage company focused on advancing a differentiated approach to ( ) islet cell replacement.

Register here: https://lifescievents.com/event/slw8y4u/

09/08/2026

We have entered into a definitive merger agreement with Seraxis to form a new company focused on the clinical advancement of a differentiated approach to islet cell replacement.

By combining our Cell Pouch Bio-hybrid Organ with Seraxis’ stem cell-derived pancreatic islet cells and in-house cGMP manufacturing, we believe we are uniquely positioned to reduce or eliminate chronic immunosuppression and address key challenges in islet cell replacement therapy for to deliver greater impact for the communities we serve.

A webinar featuring Jonathan Rigby, President and CEO of Sernova and proposed CEO of the combined company, and Will Rust, PhD, President and CEO of Seraxis and proposed President and Chief Scientific Officer of the combined company, will be held on September 11 at 10 a.m. EDT.

Learn more about the agreement and register for the webinar by reading our press release: https://bit.ly/4idbcbp

06/24/2026

Did you know, beta cells are responsible for producing insulin, the hormone that helps regulate blood glucose levels? In people living with ( ), these insulin-producing cells are destroyed by the immune system.​

With our Cell Pouch bio-hybrid organ, we aim to support the long-term survival and function of therapeutic cells to help reduce the burden of T1D. Learn more about our approach: https://sernova.com/our-focus/type-1-diabetes/

Address

Sernova Biotherapeutics 700 Collip Circle, Ste 114
London, ON
N6G4X8

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