Ractigen Therapeutics

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0193590
08/03/2018

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0193590

Short-activating RNA (saRNA), which targets gene promoters, has been shown to increase the target gene expression. In this study, we describe the use of an saRNA (Flt a-1) to target the flt-1 promoter, leading to upregulation of the soluble isoform of Flt-1 and inhibition of angiogenesis. We demonst...

08/03/2018

Short-activating RNA (saRNA), which targets gene promoters, has been shown to increase the target gene expression. In this study, we describe the use of an saRNA (Flt a-1) to target the flt-1 promoter, leading to upregulation of the soluble isoform of Flt-1 and inhibition of angiogenesis. We demonst...

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