Lipotype

Name: Lipotype
Address: Tatzberg 47, Dresden, 01307, DE
Telephone: +493512598950

Researchers of , the leading lipidomics service provider, explain and what happens

09/06/2026

New publication: Mosquito viruses hijack human entry receptors through lipid adaptation
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Mosquito-derived alphaviruses face a problem: insect and human cell membranes have different lipid compositions. Yet Chikungunya, O'nyong'nyong, and Sindbis viruses jump species efficiently anyway. A recent study reveals how they overcome this barrier by exploiting a more versatile receptor.

TIM-1 is a human immune receptor that recognises viruses by binding phosphatidylserine (PS) on viral envelopes. Mosquito-derived alphaviruses contain elevated PS and phosphatidylethanolamine (PE), both of which TIM-1 can engage. This expanded lipid recognition enhances viral entry into human cells and reveals how differences between insect and mammalian membranes influence transmission.

Lipotype's mass spectrometry platform enables comprehensive analysis of viral lipidomes.

Read the full publication here: https://www.lipotype.com/lipidomics-resource-center/?q=TIM-1%20promotes%20infection%20with%20mosquito%20cell-derived%20alphaviruses%20through%20virion-associated%20phospholipids

04/06/2026

New case study: Subcellular lipidomics in Niemann-Pick Disease Type C1
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Niemann–Pick disease type C1 (NPC1) is a genetic disorder in the group of lysosomal storage diseases. It is also considered a rare disease. In NPC1, cells lose the ability to transport lipids out of late endosomes and lysosomes, leading to progressive damage across multiple organs and systems, including the central nervous system, liver, and spleen. Using subcellular lipidomics, researchers showed that NPC1 pathology is driven by compartment-specific lipid mislocalization, rather than a uniform cellular defect.

Lipidomics Analysis by Lipotype supports the identification of lipid-driven mechanisms underlying disease pathology and intracellular lipid homeostasis.

Read the article here:
https://www.lipotype.com/lipidomics-applications/subcellular-lipidomics-in-niemann-pick-disease-type-1-npc1/

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02/06/2026

New publication: Active lipid curvature regulation in eukaryotic membranes
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Extreme hydrostatic pressure, comparable to deep-ocean conditions, reduces phospholipid curvature in living cells and serves as a precise tool to study membrane lipid regulation. A new study applied this approach in yeast and human cells, showing that both actively compensate by upregulating distinct high-curvature lipid species as a conserved metabolic response to membrane stress. The findings support a model in which cells actively maintain membranes in a "frustrated state" of curvature balance, a dynamic proposed to be critical for membrane trafficking, vesicle budding, and fusion.

Lipidomics Analysis by Lipotype supports the identification of lipid-driven mechanisms underlying membrane biology and lipid homeostasis.

Read the full publication here:
https://www.lipotype.com/lipidomics-resource-center/?q=Active%20regulation%20of%20intrinsic%20curvature%20by%20eukaryotic%20phospholipid%20metabolism

29/05/2026

May 30th is World Multiple Sclerosis Day
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Around 3 million people worldwide live with Multiple Sclerosis (MS), yet diagnosis remains slow, as highly variable symptoms often mean years before confirmation. A lipidomics study of genetically matched twin pairs showed that specific ether phospholipids (PC O- and PE O-) in blood plasma are consistently altered in MS, regardless of treatment status. This treatment independence is key: it confirms the lipid changes reflect the disease, not its management.

Identifying such accessible blood biomarkers could accelerate diagnosis and enable better treatment monitoring. Lipotype's shotgun lipidomics platform enables molecular-resolution profiling of blood plasma to identify disease-specific lipid signatures.

Read more about lipids and MS here: https://www.lipotype.com/lipidomics-applications/lipid-biomarkers-for-multiple-sclerosis/

26/05/2026

Join the Rare Disease Advances Science Communication Celebration
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On May 27, five researchers from around the world will take the stage to share their research in rare diseases through short talks as part of the Rare Disease Advances Science Communication Award hosted by scientifyRESEARCH.

Lipotype is proud to sponsor this initiative, which gives a spotlight to clear and engaging science communication and supports researchers working on rare diseases.

The award winner will be announced during the live webinar on May 27.

More info about the award here: https://www.scientifyresearch.org/event/research-to-impact-science-communication-celebration-webinar/

20/05/2026

We Are Hiring!
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Lipotype is looking for a Finance and Operations Assistant to join us! Want to be part of a biotech company shaping the future of health by preventing diseases? Apply now!

🔍 What you'll do:
• Support the finance team with daily accounting tasks, reporting, and data management.
• Assist in purchasing processes, including order handling, supplier communication, and documentation.
• Provide administrative support across operational processes and internal coordination.

🔬 We're looking for candidates who:
• Have a strong interest and first working experiences in finance, business administration and procurement.
• Are fluent in German and English and have good communicational skills.
• Have proficiency in MS Office (especially Excel) and ideally experience with DATEV or other accounting and controlling software.

🌱 Why Lipotype?
• Dynamic start-up environment with down-to-earth colleagues & flat hierarchies.
• Attractive salary, benefits & company pension scheme.
• Flexible working hours & fun team events!

Ready to make an impact? Apply now at [email protected]

Find more information: https://www.lipotype.com/2026/05/job-offer-finance-and-operations-assistant-f-m-d/

19/05/2026

Company news: Oliver Uecke on the Biology Career Insights podcast
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Turning scientific discovery into practical solutions depends on more than strong research alone. In a recent episode of the Biology Career Insights podcast, Lipotype COO Dr. Oliver Uecke shares lessons from building bridges between science, business, and innovation ecosystems.
In conversation with host Dr. Manish Kumar, he discusses commercialisation realities, the value of regional networks such as biosaxony, and the mindset required to operate across disciplines. The episode provides grounded guidance for those navigating career paths beyond the lab.

Read the details here: https://www.lipotype.com/corporate-news/bridging-science-and-business-oliver-uecke-featured-on-the-bci-podcast/

11/05/2026

Lipotype offers Skin Lipidomics
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The skin barrier is more than a physical shield; it is a lipid‑driven system regulating hydration, transepidermal water loss, and inflammatory balance. Skin lipidomics reveals how coordinated changes across many structural and signaling lipid classes drive barrier dysfunction in diseases such as eczema and psoriasis, helping explain the close link between barrier disruption and inflammation.

Lipotype Skin Lipidomics applies standardised, high‑coverage workflows to quantify a broad spectrum of structural and signalling lipid classes in skin tissue, keratinocytes, and tape‑strip samples, capturing lipid classes, subclasses, and molecular species. Lipotype Skin Lipidomics helps identify disease‑associated lipid signatures, provides insight into underlying mechanisms, and supports biomarker discovery and the development of targeted skincare and therapeutic strategies.

Read more about Skin Lipidomics here:
https://www.lipotype.com/product-groups/skin-lipidomics/

06/05/2026

Meet us at Suppliers’ Day 2026 in New York City, USA
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Join us at Suppliers’ Day 2026, the leading global event for cosmetic and personal care product development, taking place at the Javits Center in New York City.

Lipids are fundamental to skin structure, barrier function, and cellular signalling, and lipidomics provides a precise way to study these processes at the molecular level. Our account managers, Marta Vicini and Dr. Alessia Trimigno, will be available to discuss how quantitative, mass‑spectrometry‑based lipidomics supports robust study design and meaningful biological interpretation in skin and cosmetic research.

We look forward to connecting with you at booth 1480 from May 19th to 20th!

For more information: https://nyscc.org/suppliers-day/

04/05/2026

May is Mental Health Awareness Month
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Mental health is often discussed in terms of stress, environment, and support systems, but brain biology is equally important. The human brain is more than 50% lipid by dry weight, and these lipids support membrane structure, cell signalling, and communication between neurons and glial cells. When this lipid balance is disrupted, so too is the foundation of healthy brain function.

Cholesterol and phospholipids enable neuronal signalling, while sphingolipids in glial cells support myelination, immune regulation, and neural homeostasis, processes increasingly linked to mental and neurological disorders.

During Mental Health Awareness Month, it’s worth remembering that understanding mental health also means understanding the molecular composition of neural cells. Lipotype lipidomics helps researchers quantify and interpret lipid alterations that may contribute to neurological and mental disorders.

Read more about lipid profiles of neurons: https://www.lipotype.com/lipidomics-applications/lipids-of-neurons-glia-cells/

Adresse

Tatzberg 47
Dresden
01307

Telefon

+493512598950

Webseite

http://www.lipotype.com/

Benachrichtigungen

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