You Do Bio

You Do Bio You Do Bio helps researchers in the life science field.

mostly those doing genomics research, by spreading the word about great research tools and new enabling technologies that should make research easier, more relialble and hopefully more fun

A decent result. Gluten free bagels
18/08/2023

A decent result. Gluten free bagels

Handle desalting columns with the convenient and easy LabRack.
06/07/2023

Handle desalting columns with the convenient and easy LabRack.

LabRack for all CentriPure Gel Filtration Columns

Did you know that we offer a complete range of chemicals and phosphoramidites for nucleic acid synthesis?
06/07/2023

Did you know that we offer a complete range of chemicals and phosphoramidites for nucleic acid synthesis?

5% DCA in methylene chloride for Äkta oligopilot. Detritylization reagent for nucleic acid synthesis. Available in small volumes or bulk.

Let's talk about molecular sieves.No really - I mean it.Yes, you might think they look kind of boring, sitting there, do...
07/06/2023

Let's talk about molecular sieves.
No really - I mean it.
Yes, you might think they look kind of boring, sitting there, doing nothing, resembling stones or grains of sand...
..but a lot of molecular biology (I mean, A LOT) depends upon molecular sieves.
Let me explain why.
Moisture is poison when you are chemically synthesizing oligonucleotides - and oligos are at the core of so much molecular biolody.

Reagents for oligo synthesis need to be moisture-free, otherwise all kinds of bad stuff can happen - reduced reaction efficiency, unwanted side reactions, premature activation of reactive side groups on phosphoramidites.

In short, if you want purer, high-quality oligonucleotides, you need to maintain low moisture content during their chemical synthesis.

This is where molecular sieves come in.

However... molecular sieves are a bit of a pain to work with. They need to be cared for, prepared, stored correctly. You need to pre-condition and activate them before use (this involves baking them at high temperature).

If you need dry solvents, you need molecular sieves, but do you want to spend your time "baking sand" when you could be "making DNA?"
Of course not - and this is where EZ Dry moisture traps come in.

EZ Dry's consist of sachets of dry, pre-conditioned molecular sieves. You receive them, vacuum-packed, ready to use. Just open the pack, drop them in your solvent, where they will adsorb moisture, allowing you to make oligos. They come in different pack sizes, depending on solvent volume, covering most working volumes found in oligo synthesis labs.

Automated workflow in the lab facilitates large scale use of quantitative DBS and remote sampling. Capitainer recently l...
01/06/2023

Automated workflow in the lab facilitates large scale use of quantitative DBS and remote sampling. Capitainer recently launched a fully automated quantitative DBS sample handling system that enables large-scale screening and diagnostics using the company’s dried blood spot self-sampling devices. The new system, PA496, reduces the number of manual steps required when preparing Capitainer samples for analysis, thus saving valuable time and personnel resources. The first PA496 unit has already been installed in the Affinity Proteomics-Stockholm Unit at SciLifeLab, a leading Swedish research centre.

Learn more about the system and the possibilities for the lab in our new blog post.
https://capitainer.se/large-scale-dried-blood-spot-testing-possible-with-capitainers-automated-quantitative-dbs-sample-handling-system/

Our supplier Canvax Reagents can deliver all your buffer requirements - even GMP
01/06/2023

Our supplier Canvax Reagents can deliver all your buffer requirements - even GMP

This is a shout out to all the bioprocess engineers out there. Did you know that it's possible to Clarify and Capture in...
27/03/2023

This is a shout out to all the bioprocess engineers out there. Did you know that it's possible to Clarify and Capture in a single step?
Find out how, here: https://www.youdobio.com/smart/

13/06/2022
26/05/2022

A great video explaining SMART Chromatography™

You don't have to do this to get a good quality sample for COVID-19 testing. Just use saliva. There are good, dare I say...
23/02/2021

You don't have to do this to get a good quality sample for COVID-19 testing.

Just use saliva. There are good, dare I say awesome, saliva collection kits that have been proven to work in COVID-19 testing.

Aarhus Universitetshospital er i gang med at afprøve en hjemmetest for coronavirus. Man håber at have vurderet testens pålidelighed inden for fire uger, fortæller overlæge.

Dear Denmark, saliva is an unbeatable way to collect samples for COVID-19 screening. I recommend you read this:Astra Zen...
23/02/2021

Dear Denmark, saliva is an unbeatable way to collect samples for COVID-19 screening. I recommend you read this:
Astra Zeneca published a study on their efforts to test their employees for COVID-19.
The introduction of saliva instead of swabs is described as "transformative."
They switched from swabs to saliva because swabs "proved to be uncomfortable and unpopular, leading to lower adoption than required."
Following the introduction of saliva testing, adoption by employees increased approximately 4-fold.
(of course I'm biased - I sell GeneFix Saliva collection kits - but that's because they work)
Article can be downloaded here:

https://assets.researchsquare.com/files/rs-246781/v1/1b42cfd8-dfa5-453c-b6ec-5ab1673a0c61.pdf

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