29/05/2026
Today Dr. Alexandre Calon (Head of the Translational Research in Tumor Microenvironment Laboratory) has given a seminar at IPBLN.
Titled: ‘Beyond Cancer Cells: The Tumor Microenvironment in Precision Oncology’.
The lecture has explored the role of the tumor microenvironment in cancer progression and treatment response. It has highlighted recent findings on how cancer-associated fibroblasts shape therapy resistance, tumor immunity, and the development of precision oncology strategies.
Alexandre Calon leads the Translational Research in Tumor Microenvironment (TReaTME) laboratory at the Hospital del Mar Research Institute (IMIM, Barcelona, Spain). His research focuses on how tumor–stroma interactions influence metastasis and therapy resistance, particularly in colorectal and breast cancer. The lab combines patient-derived organoids, primary stromal cells, humanized immunocompetent models, and molecular profiling of patient samples to study cancer-associated fibroblasts, immune regulation, and mechanisms of treatment response. Projects are closely integrated with prospective patient studies and clinical trials, aiming to advance clinically relevant biomarkers and personalized medicine.
