11/06/2026
🌟Application note! Differentiation of induced pluripotent stem cells (iPSCs) into astrocytes
Astrocytes are the most abundant glial cells in the human central nervous system and are essential for maintaining healthy brain function. They regulate neurotransmitter uptake, ion and metabolic homeostasis, synaptic activity, and blood–brain barrier integrity, while also contributing to neuroimmune signaling, inflammation, injury response, and neuronal survival.
Increasing evidence links astrocytic dysfunction to the pathogenesis of numerous neurological and neurodegenerative diseases, including Alzheimer’s disease, amyotrophic lateral sclerosis (ALS), Parkinson’s disease, and epilepsy.
Consequently, physiologically relevant human astrocyte models are essential for advancing our understanding of CNS biology, disease mechanisms, and for drug discovery and neurotoxicity testing.
Read our application note using Qkine growth factors to differentiate iPSC into astrocytes > https://zurl.co/Zw4KZ
We have grouped the growth factors needed for astrocyte differentiation into a differentiation kit, saving over 30% on buying them individually > https://zurl.co/F8tcK
Astrocyte differentiation uses
Thermostable FGF-2 (FGF2-G3, Qk052) > https://zurl.co/n0evB
Noggin (Qk034) > https://zurl.co/pyPkP
EGF (Qk011) > https://zurl.co/vLUUd
CNTF (Qk063) > https://zurl.co/7yj4K
All Qkine growth factors are animal origin-free, highly bioactive and guaranteed to be reproducible lot-to-lot.