Promega UK

Promega UK UK Promega life sciences team, sharing technical tips, event info, news, articles and blog posts.

We are the Promega UK branch and we are looking forward to serving and supporting your research! As a renowned innovator of reagents and consumables for life sciences, drug discovery, genetic identity, clinical and applied sciences, we have more than 3,000 products and a growing portfolio of custom offerings and OEM solutions. We hope to enable you to advance your research with our products and o

ur support ! For any technical advice or queries please contact our Technical Services team at [email protected]

The 11th International Conference on Legionella takes place next week!Marking 50 years since the discovery of Legionella...
04/09/2026

The 11th International Conference on Legionella takes place next week!

Marking 50 years since the discovery of Legionella, the conference will explore the latest in research across areas such as diagnostics, epidemiology and environmental science.

Promega will be exhibiting, so if you’re attending, visit their stand to meet the team and learn more about how our solutions could support your research.

Traditional metabolic research captures a snapshot after cells are lysed. But metabolic disease is dynamic, involving in...
03/09/2026

Traditional metabolic research captures a snapshot after cells are lysed. But metabolic disease is dynamic, involving interconnected networks of metabolites, enzymes, and signalling molecules.

A new analysis of eighteen peer-reviewed publications reveals a significant shift: researchers are adopting bioluminescent tools that capture real-time, multi-pathway responses.

Live-cell approaches like NanoBRET and HiBiT-based assays enable researchers to watch protein behaviour and drug engagement directly in living cells. Glo-based metabolite detection assays offer faster, more sensitive detection with shared formats, making multi-pathway analysis practical.

Understanding metabolic disease requires measuring metabolism dynamically, in context, and across multiple pathways.

Read the full blog: https://ow.ly/Toqb50ZuXyt

Do you need to detect and sort your HiBiT-tagged proteins by flow cytometry?The Anti-HiBiT monoclonal antibody fluoropho...
02/09/2026

Do you need to detect and sort your HiBiT-tagged proteins by flow cytometry?

The Anti-HiBiT monoclonal antibody fluorophore conjugates provide sensitive, specific signal from XFD dyes.

No secondary antibody required, compatible with fixed and live-cell flow cytometry.

Available in Green 488 and Far Red 647.

Learn more at: https://ow.ly/g6sR50ZuWJ3

Reminder: Free webinar tomorrow, Wednesday, 2 September 2026 at 3.00 p.m. (BST)Hold and Kill: An Integrated Assay Strate...
01/09/2026

Reminder: Free webinar tomorrow, Wednesday, 2 September 2026 at 3.00 p.m. (BST)

Hold and Kill: An Integrated Assay Strategy for RIPTAC, an Emerging Induced-Proximity Modality

RIPTACs represent a breakthrough "hold-and-kill" approach already in clinical trials. Learn how NanoBRET® characterises ternary complex formation and how assay strategies support RIPTAC developability.

Don't miss it!

Register at: https://event.on24.com/wcc/r/5451925/9F2037BF533760922D49C27A94150270?partnerref=newcommun

27/08/2026

Lumie's always ready when our LinkedIn Newsletter drops. 👀

Our monthly LinkedIn Newsletter is packed with fresh insights, expert perspectives, and industry updates.

Subscribe so you never miss an edition at: https://ow.ly/Ibri50ZG5Nb

Fc Effector Insight: Integrated Fc Effector WorkflowDownload the Fc Receptors: Function Analysis and Characterisation gu...
27/08/2026

Fc Effector Insight: Integrated Fc Effector Workflow

Download the Fc Receptors: Function Analysis and Characterisation guide to see how Promega supports effector characterisation from lead generation through lot release.

The guide covers Lumit® Fc receptor binding immunoassays, ADCC/ADCP Reporter Assays with engineered effector cells, and HiBiT® Target Cell Killing Bioassays for physiologically relevant readouts.

Download today at: https://ow.ly/ESsx50Zgb2b

Free webinar: Wednesday, 2 September 2026 at 3.00 p.m. (BST) - Hold and Kill: An Integrated Assay Strategy for RIPTAC, a...
26/08/2026

Free webinar: Wednesday, 2 September 2026 at 3.00 p.m. (BST) - Hold and Kill: An Integrated Assay Strategy for RIPTAC, an Emerging Induced-Proximity Modality

RIPTACs represent a new frontier in targeted protein degradation. A heterobifunctional molecule holds a tumour-specific target and a pan-essential effector together in a ternary complex, silencing the essential protein only in cells carrying the target.

An AR-BRD4 RIPTAC is already in Phase 1/2 trials for metastatic castration-resistant prostate cancer, with PSA responses in patients who failed prior therapies.

Join Promega and ICE Bioscience to explore characterising RIPTAC mechanisms using NanoBRET® to measure ternary complex formation and assay strategies for developability assessment.

Register at: https://ow.ly/a9by50ZwzXB

Most protein detection methods require you to kill your cells first. Fixation, lysis, blotting – just a snapshot.HiBiT b...
25/08/2026

Most protein detection methods require you to kill your cells first. Fixation, lysis, blotting – just a snapshot.

HiBiT bioluminescence works differently.

The 11 amino acid HiBiT tag gives you direct, quantitative readout of your endogenous protein in live cells for protein secretion, degrader-induced protein loss, and receptor trafficking.

Learn more: https://ow.ly/jXn250ZuKZN

Our assay-ready Thaw-and-Use cells are validated for potency testing of monoclonal antibodies targeting FcγR (ADCC/ADCP)...
24/08/2026

Our assay-ready Thaw-and-Use cells are validated for potency testing of monoclonal antibodies targeting FcγR (ADCC/ADCP), Checkpoint Inhibitors (PD-1/PD-L1, 4-1BB), and Cytokine-GF Receptors (e.g., IL-1, VEGF).

With batch sizes of up to 1,000 vials and stringent intra- and inter-batch quality controls, our Thaw-and-Use cells deliver consistent results, time after time, for QC and lot release testing.

Learn more: https://ow.ly/ErPB50ZgaHV

Earlier this year at the AACR Annual Meeting 2026, Promega presented the Lumit® hKi-67 Immunoassay for cell proliferatio...
20/08/2026

Earlier this year at the AACR Annual Meeting 2026, Promega presented the Lumit® hKi-67 Immunoassay for cell proliferation, demonstrating how bioluminescent detection optimises high-throughput screening performance.

The assay delivers rapid, sensitive measurement of Ki-67 across suspension cells, adherent cultures, and 3D spheroid systems.

The simple, wash-free protocol with excellent sensitivity and consistency makes it ideal for compound profiling.

Missed it first time around? It's worth catching up with over the summer. The peer-reviewed abstract is now available through the AACR Journals platform.

Read the abstract at: https://ow.ly/b2xN50ZgjHa

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