07/08/2026
🔬 Ultrasonic Irrigation for Effective Biofilm Removal and Reduced Apical Extrusion
Effective root canal irrigation requires more than simply delivering an irrigant. Mechanical activation can improve cleaning within complex canal anatomy, but the risk of sodium hypochlorite extrusion beyond the root apex must also be considered.
A peer-reviewed in vitro study published in the Journal of Oral Science evaluated biofilm removal and the apical extrusion of sodium hypochlorite using a standardized 3D-printed root canal model containing human dentin specimens.
The study compared conventional syringe irrigation, low-frequency sonic activation, high-frequency sonic activation, and ultrasonic activation with Endosonic Blue2.
The results showed that Endosonic Blue2 and the high-frequency sonic activation system achieved effective biofilm removal, with a greater number of exposed dentinal tubules observed after irrigation.
Key findings included:
✅ Effective reduction of intracanal biofilm
✅ More exposed dentinal tubules after irrigation
✅ Biofilm removal comparable to the high-frequency sonic activation system
✅ Significantly less apical extrusion of NaOCl than the high-frequency sonic activation system
✅ A favorable balance between cleaning efficacy and apical extrusion control
✅ Potential as a machine-assisted root canal irrigation system
The researchers concluded that ultrasonic activation with Endosonic Blue2 effectively reduced intracanal biofilm while resulting in less apical extrusion of sodium hypochlorite than the high-frequency sonic activation system.
Endosonic Blue2 goes beyond irrigant activation, supporting effective cleaning within complex root canal anatomy while taking apical extrusion into consideration.
📄 Shin et al., Journal of Oral Science, 2023;65(3):187–192
🔗 DOI: 10.2334/josnusd.23-0025