Proteomics Core Facility - Rikshospitalet

20/12/2016

New publication from PCF:

http://www.sciencedirect.com/science/article/pii/S246802491630170X

Fibrinogen A alpha chain amyloidosis is an autosomal dominant disease associated with mutations in the fibrinogen A alpha chain (FGA) gene, and it is the most common cause of hereditary renal amyloidosis in the UK. Patients typically present with kidney impairment and progress to end-stage renal dis...

20/12/2016

New publication from PCF:

http://www.sciencedirect.com/science/article/pii/S1570963916302564

Nitrogen is needed for the biosynthesis of biomolecules including proteins and nucleic acids. In the absence of fixed nitrogen prokaryotes such as E. coli immediately ceases growth. Ammonium is the preferred nitrogen source for E. coli supporting the fastest growth rates. Under conditions of ammoniu...

20/12/2016

New publication from PCF:

http://pubs.acs.org/doi/abs/10.1021/acs.jproteome.6b00211

Label-free Proteomic Reveals that Cowpea Severe Mosaic Virus Transiently Suppresses the Host Leaf Protein Accumulation During the Compatible Interaction with Cowpea (Vigna unguiculata [L.] Walp.)Ana L. S. Paiva†, Jose T. A. Oliveira*†, Gustavo A. de Souza‡, and Ilka M. Vasconcelos§ †Laboratory of Pl...

19/10/2016

New publication from PCF

http://www.nature.com/mtna/journal/v5/n10/full/mtna201664a.html

Molecular Therapy — Nucleic Acids is a new international all open-access journal publishing top-quality basic, translational and clinical research in the broad fields of nucleic acid-based therapeutics to treat and/or correct genetic and acquired disease.

19/09/2016

New publication from PCF

http://pubs.acs.org/doi/abs/10.1021/acs.jproteome.6b00652

Proximity labeling reveals molecular determinants of FGFR4 endosomal transportEllen Margrethe HaugstenVigdis SørensenMichaela Kunová BosakovaGustavo Antonio de SouzaPavel KrejciAntoni WiedlochaJørgen WescheJ. Proteome Res., Just Accepted ManuscriptDOI: 10.1021/acs.jproteome.6b00652Publication Date (...

19/09/2016

New publication from PCF

http://www.tandfonline.com/doi/abs/10.1080/15384047.2016.1219813?journalCode=kcbt20

(2016). Comparative protein profiling of B16 mouse melanoma cells susceptible and non-susceptible to alphavirus infection: Effect of the tumor microenvironment. Cancer Biology & Therapy. Ahead of Print. doi: 10.1080/15384047.2016.1219813

29/08/2016

New publication from PCF

http://www.nature.com/nmeth/journal/vaop/ncurrent/full/nmeth.3967.html

A straightforward method and tool, MetaMass, utilizes a list of subcellular markers to analyze and classify subcellular proteomics data from multiple experiments. An accompanying analysis reveals a wide variation in the results of subcellular fractionation protocols.

08/05/2016

New publication from PCF

http://www.nature.com/articles/srep25565

This study aimed to identify proteolytic fragments of gluten proteins recognized by recombinant IgG1 monoclonal antibodies generated from single IgA plasma cells of celiac disease lesions.

28/12/2015

New publication from PCF

http://www.sciencedirect.com/science/article/pii/S1874391915302062

Evidence that persistent environmental pollutants may target the male reproductive system is increasing. The male reproductive system is regulated by secretion of testosterone by testicular Leydig cells, and perturbation of Leydig cell function may have ultimate consequences. 3-Methylsulfonyl-DDE (3…

13/12/2015

New publication from PCF

http://www.mcponline.org/content/early/2015/12/04/mcp.M115.050138.long

02/10/2015

New publication using data collected at PCF

http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134922

A hallmark of the gluten-driven enteropathy celiac disease is autoantibody production towards the enzyme transglutaminase 2 (TG2) that catalyzes the formation of covalent protein-protein cross-links. Activation of TG2-specific B cells likely involves gluten-specific CD4 T cells as production of the…

02/10/2015

New publication using data collected at PCF

http://www.sciencedirect.com/science/article/pii/S001650851501001X

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