16/05/2026
Imdermalab® Supra-SA
INCI: Salicylic Acid, PEG-15 Cocamine, Stearamidopropyl Dimethylamine
• Alcohol free
• Anti-acne
• Milder to skin than traditional Salicylic acid
*acne formation*
1.Genetic factors play an important role in the development of acne, especially severe acne.
2. Hormone secretion Androgens are the main triggers of sebaceous gland hyperplasia and massive lipid secretion. Other hormones such as insulin-like growth factor -1 ( IGF-1 ), insulin, growth hormone, etc.
may also be related to the occurrence of acne.
3. Sebaceous glands secrete lipids
Excessive secretion of lipids by sebaceous glands is considered to be a prerequisite for the occurrence of acne, but changes in lipid components, such as increased squalene peroxide, wax esters, free fatty acid content, increased proportion of unsaturated fatty acids, and decreased linoleic acid content, can also cause acne. important factors that occur.
4. Bacterial infection
Hair follicle microorganisms such as Propionibacterium acnes are involved in the occurrence of acne through natural immunity and acquired immunity. Malassezia can cause hair follicle infection, turning into follicular red papules or pustules on the chest and back.
5. Inflammatory reaction
Hair follicle microorganisms and / or abnormal lipids activate Toll- like receptors ( TLRs ) to produce interleukin ( IL ) -1α and other related inflammatory transmitters. IL-1α is currently considered to be responsible for keratinization of sebaceous gland ducts and the formation of microcomedones and acne. main factors.
Acne Classification
If the skin secretes too much sebum, whiteheads will easily form on the skin, and after the oil is oxidized, it will turn into blackheads. When the inflammation is close to the surface of the skin or deeper , pustules and papules will appear . If the inflammation is deeper, cysts will form.
Pillsbury classification divides acne into 4 levels :
Mild ( Grade 1 ): Acne and blackheads
Moderate ( Grade 2 ): Inflamed papules
Moderate ( Grade 3 ): pustules
Severe ( Grade 4 ): nodules, cysts