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29/05/2026

🧬 Prime editing is rapidly emerging as a powerful genome engineering approach, enabling precise insertions, deletions, and base substitutions without introducing double-strand DNA breaks (DSBs).

To support next-generation gene editing research, CROYEZ PEmax mRNA is designed to provide:

✅ DNA-free mRNA delivery
✅ Transient expression for greater temporal control
✅ An optimized PEmax architecture with enhanced nuclear localization
✅ Compatibility with sensitive and primary cells, including T cells, HSPCs, and iPSCs

Compared with conventional plasmid-based workflows, mRNA delivery enables transient editor expression without relying on prolonged DNA-based expression, offering researchers a flexible option for advanced genome engineering applications.
Whether you're working on cell engineering, functional genomics, disease modeling, or precision medicine research, PEmax mRNA may help streamline your prime editing workflow.

💬 Are you currently using plasmid-based prime editing, or are you exploring mRNA-based approaches? We'd love to hear about your experience.
🔗 Explore PEmax mRNA and the complete CROYEZ Cas9 & Gene Editing portfolio on our website：https://www.croyezbio.com/product/detail/id/842/name/PEmax%20mRNA%20(%20m1%CF%88%20substitution%20).html

顯示翻譯

18/05/2026

👉🏼 RNA workflows are evolving rapidly. As research continues expanding into:

• IVT mRNA
• saRNA workflows
• CRISPR mRNA
• Long RNA analysis

accurate RNA QC is becoming more important than ever.
At CROYEZ, we’re seeing increasing demand for reliable RNA sizing solutions supporting both routine RNA electrophoresis and modern RNA therapeutics workflows.

A few applications our RNA Ladder Series supports:
✔ Routine RNA QC
✔ IVT mRNA analysis
✔ RNA electrophoresis
✔ CRISPR mRNA workflows
✔ saRNA & long RNA analysis

Our RNA Ladder Series includes:
• RNA Ladder (6K)：https://www.croyezbio.com/product/detail/id/753/name/RNA%20Ladder.html
• Mid Range RNA Ladder (9K)：https://www.croyezbio.com/product/detail/id/824/name/Mid%20Range%20RNA%20Ladder.html
• High Range RNA Ladder (12K)：https://www.croyezbio.com/product/detail/id/754/name/High%20Range%20RNA%20Ladder.html

Designed to support reliable RNA sizing up to 12,000 nt.
We’re always happy to discuss RNA QC workflows, electrophoresis challenges, and long RNA analysis with researchers working in the RNA field.
If your team is working on RNA therapeutics, IVT workflows, or saRNA research, feel free to connect with us.🥰

07/05/2026

✨ This week is Mother’s Day ✨

A special occasion celebrated and cherished around the world 💐
Croyez would like to wish all mothers a joyful and happy Mother’s Day! ❤️
Thank you for your love, care, and endless support every day.
Feel free to share this with the amazing moms around you 🌷

04/05/2026

✨Track Mitochondria in Real Time — Without DNA Integration 🔬
Traditional mitochondrial labeling tools rely on plasmids or viral delivery.
Croyez Mito-GFP mRNA offers a faster and safer alternative.

⭐️Rapid protein expression
⭐️No genomic integration risk
⭐️Precise mitochondrial targeting via MTS
⭐️Enhanced stability with m1Ψ modification
Visualize mitochondrial morphology, fusion, and fission in live cells with clarity❗️

👉 Explore more:
https://www.croyezbio.com/product/detail/id/841/name/Mito-GFP%20mRNA%20(%20m1%CF%88%20substitution%20).html

24/04/2026

⭐️Strong GFP expression in primary T cells—yes, it’s achievable.

Primary T cells are notoriously difficult to transfect, yet CROYEZ GFP-saRNA demonstrates clear and dose-dependent reporter expression.

📊 Flow cytometry results show increased GFP-positive populations at higher RNA doses

🔬 Fluorescence and confocal imaging confirm clear GFP signals at 24 hours post-transfection

From delivery to expression, reliable results matter.

Take a look:
https://www.croyezbio.com/product/detail/id/807/name/GFP%20Self-Amplifying%20RNA%20%20%20GFP%20saRNA.html

13/04/2026

⭐️One workflow. Two powerful tools.⭐️
Croyez supports your SUMO protein workflow from cleavage to detection.

✔ Precise SUMO tag cleavage
✔ Enhanced protein solubility
✔ Sensitive residual protease detection
✔ Reliable purification monitoring

With SUMO Protease (ULP1) (Active) and the SUMO Protease (ULP1) ELISA Kit, Croyez helps streamline your SUMO fusion protein research.

➤SUMO Protease (ULP1) (Active):https://www.croyezbio.com/product/detail/id/701/name/SUMO%20Protease%20(ULP1)%20(Active).html
➤SUMO Protease (ULP1) ELISA Kit:https://www.croyezbio.com/product/detail/id/703/name/SUMO%20Protease%20(ULP1)%20ELISA%20Kit.html

07/04/2026

🧬 New Product Launch | CROYEZ Cre mRNA

In genetic engineering research, the Cre–LoxP system is one of the most widely used DNA recombination tools.

With Cre mRNA, researchers can easily perform:

🔹 Conditional gene knockout
🔹 Temporal gene control
🔹 Cell lineage tracing
🔹 Removal of editing or selection cassettes

CROYEZ Cre mRNA is produced using an optimized IVT process, enabling stable expression and efficient recombination in both in vitro and in vivo models.

If your research involves the Cre–LoxP system,
CROYEZ Cre mRNA might be a great addition to your workflow 😉
👉🏼https://www.croyezbio.com/product/detail/id/836/name/Cre%20mRNA.html

20/03/2026

🧬 CROYEZ Reporter Gene mRNA Free Trial Program

CROYEZ is launching our Reporter Gene mRNA Free Trial Program!
Researchers can apply for a free 10 μg Reporter Gene mRNA sample, perform fluorescence expression experiments, and submit the results to receive a CROYEZ online store discount voucher.

・Selected results may be featured by CROYEZ
・All participants will receive a discount voucher

Applications open on March 21, 2026

Program Details
🔗https://www.croyezbio.com/news/detail/id/34.html?utm_source=social&utm_medium=fb-in&utm_campaign=FREE-Reporter

Apply Now
📝https://user296366.pse.is/8tn4g5

04/03/2026

⭐️PRAME is gaining increasing attention as a promising target in cancer immunotherapy.
As a cancer-testis antigen (CTA), PRAME is preferentially expressed in tumors while showing minimal expression in normal tissues. This unique expression profile makes it an attractive target for T cell–based immunotherapy, vaccine development, and translational immuno-oncology research.
Through our collaboration with peptides&elephants GmbH , CROYEZ Bioscience helps bring peptide pools and custom peptide design solutions to researchers working on PRAME-related studies, including:

• PRAME peptide pools
• HLA-restricted epitopes (A02 / A24 / A03)
• MHC-I & MHC-II peptide design
• Support for antigen-specific T cell research

From antigen discovery to translational studies, these peptide solutions support a wide range of immuno-oncology research applications.

🔬 Learn more about PRAME-related peptide solutions:
🔹https://www.peptides.de/Peptide-Insights/Cancer-Testis-Antigens/PRAME/
🔹https://www.peptides.de/Peptide-Insights/MHC-I-versus-MHC-II/

06/02/2026

Croyez Fast, clean, and reliable mRNA delivery—without the extra complexity.🧪

Our EndoSafe mRNA Transfection Reagent is designed for researchers who need high transfection efficiency, rapid protein expression, and low cellular stress.

✔ Strong reporter expression across multiple mRNA types
✔ Sustained signal in time-course studies
✔ Endotoxin-conscious design for sensitive and immune-related cells
✔ Simple, single-reagent workflow—no boosters required
From HEK293T to BHK21 cells, EndoSafe delivers consistent performance for both mRNA and saRNA applications.

Articles:
https://www.croyezbio.com/support/detail/id/158.html

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https://www.croyezbio.com/

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