ISS Inc

06/05/2026

Perovskite performance is often determined by what you can't see.

📩 Interested in fluorescence lifetime, photoluminescence lifetime imaging (PLIM), phasor analysis, anisotropy, and time-resolved spectroscopy as they relate to semiconductors, perovskites, photovoltaics, quantum dots, nanomaterials, phosphors, upconversion materials, 2D materials, and/or energy devices? Let's talk, reach out here: https://iss.com/contact

Local defects, trap states, and carrier recombination pathways can dramatically impact solar cell efficiency and long-term stability.

The ISS PL1 enables high-resolution photoluminescence lifetime imaging (PLIM) of perovskite materials, helping researchers identify spatial variations in lifetime that correlate with material quality and device performance.

Find out more about PL1 here: https://iss.com/fluorescence/time-resolved-laser-scanning-confocal-microscopes/pl1

Using ISS VistaVision software and model-free phasor analysis, lifetime differences can be visualized directly from raw data without complex fitting routines.

When every nanosecond matters, lifetime imaging provides insights that intensity measurements alone cannot.

Discover why leading perovskite researchers use ISS technology to investigate carrier dynamics and defect engineering.

06/04/2026

Your photoluminescence intensity image may be hiding the most important information.

Two materials can produce nearly identical PL intensity while exhibiting dramatically different excited-state dynamics, carrier lifetimes, and defect populations.

By measuring fluorescence and photoluminescence lifetimes, researchers can uncover:

✓ Trap states and defect distributions
✓ Carrier recombination pathways
✓ Exciton dynamics
✓ Material heterogeneity
✓ Device degradation mechanisms

The ISS PL1 Material Sciences Confocal Workstation combines high-resolution photoluminescence imaging with lifetime measurements from 100 ps to 100 ms, allowing researchers to visualize both intensity and lifetime variations across their samples.

Because understanding how long an excited state survives is often just as important as knowing how bright it is.

Find out more here: https://iss.com/fluorescence/time-resolved-laser-scanning-confocal-microscopes/pl1

06/03/2026

Focus and Discover

At ISS, these three words represent more than a tagline they represent a philosophy of scientific discovery.

Focus on the details that matter. Find out more here: https://iss.com/

Discover the information hidden beyond intensity images.

For more than 40 years, ISS has developed advanced fluorescence instrumentation that helps researchers move beyond simply visualizing biological structures to quantitatively understanding the molecular mechanisms that drive them.

From high-performance confocal imaging and super-resolution microscopy to FLIM, FFS, FRET, phasor analysis, and single-molecule measurements, ISS technologies are designed to reveal information that conventional imaging often cannot.

🔹 Focus on cellular structure.
🔹 Discover molecular interactions.

🔹 Focus on fluorescence intensity.
🔹 Discover lifetime signatures, diffusion dynamics, and protein organization.

🔹 Focus on an image.
🔹 Discover the quantitative biology behind it.

Whether you're studying protein interactions, cellular metabolism, molecular diffusion, phase separation, super-resolution imaging, or fluorescence lifetime dynamics, ISS provides the tools to transform photons into meaningful scientific insight.

Because great microscopy doesn't just help you see your sample.

It helps you understand it.

ISS...Focus and Discover!

06/02/2026

The data shown here demonstrates Photon Counting Histogram (PCH) analysis of cohesin complexes in live yeast cells, revealing important insights into protein stoichiometry throughout the cell cycle.

Using GFP monomer and GFP dimer constructs as molecular brightness standards, researchers were able to compare the brightness of SCC1-GFP and determine its oligomeric state in living cells. The results showed that cohesin predominantly exists in a monomeric form, while also enabling investigation of how regulatory proteins such as Wpl1, Pds5, and Eco1 influence cohesin organization and function.

📩 Interested in protein stoichiometry, oligomerization studies, or advanced fluorescence fluctuation spectroscopy? Let's talk, reach out here: https://iss.com/contact

🧪 What is Photon Counting Histogram (PCH) Analysis?

PCH is a powerful extension of Fluorescence Fluctuation Spectroscopy (FFS) that analyzes the statistical distribution of detected photons over time.

Rather than focusing solely on molecular diffusion, PCH quantifies:

✔️ Molecular brightness
✔️ Oligomeric state
✔️ Protein stoichiometry
✔️ Molecular heterogeneity
✔️ Population distributions within living cells

Because molecular brightness scales with the number of fluorescent molecules moving together, PCH can distinguish between monomers, dimers, and larger molecular assemblies.

PCH analysis is particularly valuable for studying:

• Protein-protein interactions
• Oligomerization and aggregation
• Transcription factor assembly
• Receptor clustering
• Chromatin-associated complexes
• Cell-cycle dependent molecular organization

For researchers investigating how molecular complexes assemble and function inside living cells, PCH provides quantitative evidence that goes beyond localization alone.

PCH is integrated into the broader ISS FFS platform, which includes:

✔️ FCS
✔️ FCCS
✔️ FLCS
✔️ Scanning FCS
✔️ RICS
✔️ Number & Brightness (N&B)

Available across ISS confocal microscopy platforms.

💬 Bottom line:

PCH transforms fluorescence fluctuations into quantitative measurements of molecular brightness and oligomeric state, helping researchers determine not just where proteins are—but how they assemble and function inside living cells.

06/01/2026

ACSM 2026 is a wrap and we left Salt Lake City with a lot of great research conversations and a clear takeaway. The sports medicine research community is asking better and better questions about measurement methodology. Across every conversation at Booth #716, the core question kept surfacing in different forms:

"How do I know my NIRS data actually reflects what's happening in the tissue and not just my calibration assumptions?"

That question is exactly what the OxiplexTS was designed to answer.

If we met at the show and you want to continue the conversation — or if you didn't make it to the booth and want to see a virtual demonstration — reach out directly here: https://iss.com/contact

We can schedule a brief online overview that walks through the system, the data output, and how it fits your specific research application. No commitment required.

Looking forward to seeing what comes out of this year's ACSM research and hopefully being part of the work that follows.

🔗 Find out more about our biomedical instruments here: https://iss.com/biomedical

05/29/2026

A study in the Journal of Human Kinetics investigated how rest redistribution—breaking long rest periods into shorter, more frequent ones—affects fatigue during maximal eccentric knee extensions. 💪

To monitor muscle oxygenation throughout the exercise protocol, researchers relied on the ISS OxiplexTS, a powerful NIRS device that delivers real-time insights into tissue oxygenation and hemodynamics. 📈

The study found that rest redistribution influences fatigue and muscle performance, offering valuable insights for athletic training and rehabilitation strategies.

📖 Read the full publication: https://pmc.ncbi.nlm.nih.gov/articles/PMC7706641/

➡️Check out the OxiplexTS: https://iss.com/biomedical/oxiplexts

If your research involves muscle oxygenation, oxygen kinetics, exercise physiology, or sports medicine we'd love to show you what this data actually looks like in practice.

Come find us at Booth #716. No pressure, no sales pitch. Just a quick look at the technology and a conversation about your work.

📍 Salt Lake City Convention Center
📅 May 26–29, 2026
🔬 ISS Medical Booth #716

05/28/2026

The question we've heard most at Booth #716 so far: "What does the data actually look like?"

Here's the short answer: it looks like a live, real-time trace of oxygenated and deoxygenated hemoglobin in your target tissue, updating at up to 50 times per second.

Unlike conventional NIRS devices, the OxiplexTS uses frequency-domain photon migration to independently measure both light absorption AND scattering in the tissue. That's what makes it possible to report absolute concentrations, not just relative changes from an arbitrary baseline.

For researchers, that distinction matters for:

→ Between-subject comparisons
→ Multi-site and longitudinal studies
→ Grant applications where reviewers want methodology rigor
→ Publications in high-impact journals where limitations sections get scrutinized

We have two days left on the exhibit floor. If you haven't stopped by yet...Booth #716, Salt Lake City Convention Center. The system is on.

📅 Open through Friday, May 29

05/27/2026

We're live at ACSM 2026!
Day one on the exhibit floor. Booth #716 is open, the system is running, and we're ready to talk tissue oxygenation with anyone who wants to stop by.

This year's ACSM spotlight — Physical Activity, Exercise & Technology — could not be a better fit for what we do. Frequency-domain near-infrared spectroscopy is exactly the kind of advanced measurement technology that's pushing exercise science forward: non-invasive, quantitative, and validated across 150+ peer-reviewed studies.

If you're here in Salt Lake City and want to see what absolute muscle oxygenation data looks like in real time — no relative changes, no assumptions, no calibration — come by between sessions.

We'll keep it brief. You'll leave with a clear sense of whether this fits your research.

📍 ISS Medical · Booth #716
📅 Today through Friday, May 29

05/26/2026

SPORTS MEDICINE RESEARCH WITH OXIPLEXTS
The OxiplexTS, a non-invasive near-infrared tissue oximeter, supports a range of research applications in Sports Medicine. In this publication, it was used to investigate whether athletes, such as cyclists, with high-affinity hemoglobin (HAH) exhibit reduced skeletal muscle deoxygenation during exercise under both normoxic and hypoxic conditions.

Read the full publication here: https://physoc.onlinelibrary.wiley.com/doi/epdf/10.1113/EP090308

Additional OxiplexTS publications: https://iss.com/biomedical/oxiplexts

If your research involves muscle oxygenation, oxygen kinetics, exercise physiology, or sports medicine we'd love to show you what this data actually looks like in practice.

Come find us at Booth #716. No pressure, no sales pitch. Just a quick look at the technology and a conversation about your work.

📍 Salt Lake City Convention Center
📅 May 26–29, 2026
🔬 ISS Medical Booth #716

05/22/2026