Phage Display Libraries
Phage display is a high-throughput technology that is used to discover polypeptide-based ligands. The phage particles are genetically engineered to display random sequences on the viral coat proteins. Smith at the University of Missouri, for which he was later awarded the Nobel Prize in Chemistry (2018). Specifically, he used filamentous phage to create a library of random
displayed peptides. We currently carry a linear 15-mer peptide library (fUSE5) based on the original phage display systems by Dr. George Smith. This random peptide library exhibits excellent diversity and is proven to result in selection of high-specificity ligands with numerous research articles evidencing its efficacy. Do you need a custom phage display library? Cell Origins will work directly with you to customize and build a phage display library. We can build optimized selection and tagging strategies into your library to facilitate selection of high-specificity ligands and to perform quicker and more accurate analysis of selected phage clones post screening. Need help with your phage display research strategy? Our team at Cell Origins are experts in phage display technology. We have over 40 years of experience developing phage display and peptide research strategies that have led to numerous publications and research grants. We will develop a detailed research strategy that you can use for a convincing grant proposal and for optimal selection of high-specificity ligands. To provide you with the best service, we offer a free meeting to learn more about how we can help your project succeed. Please contact us to learn more and to schedule a meeting with one of our scientists. Let us carry out your phage display screening
Cell Origins offers proven and published phage display screening by our leading experts in the fields. We will customize a biopanning strategy to provide high-specificity ligands that bind your target of choice. We have unsurpassed experience in selection of peptides that exhibit excellent biodistribution with minimal uptake in non-target tissues. However, we also carry out screening against non-biological materials, as well as under harsh conditions. Our scientist will work directly with you to tailor the most optimal strategy using one of our own phage display libraries or a library of your choice. We will carry out the phage display experiments in our laboratory that is designed for precise and accurate selections.
