10/19/2026
🧬🫸 Where will next-generation inhibitors, targeted protein degradation (TPD), and combo therapies take the study of cell proliferation? Completely halting proliferative signaling is challenging due to pathway redundancy, resistance, and rewiring. Discover how recent advances in drug design are overcoming this challenge to create more effective, targeted cancer treatments. Learn more about the Cancer Hallmark: Sustaining Proliferative Signaling on the .
A Hallmark of Cancer, sustaining proliferative signaling is used by cancer cells to stimulate growth and relies on Akt, MAPK/Erk, and MTOR pathways.