09/01/2026
A team at Lund University found how heme can trigger a chain reaction in the blood that activates inflammation, making blood vessels more permeable. Their findings could have implications for conditions involving the breakdown of red blood .
Heme is released from red blood cells during hemolytic uremic syndrome (HUS). Here, we investigated hemolysis-induced kallikrein-kinin system activation and the interaction between heme and clotting factor XII (FXII).