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EpiCypher Inc. EpiCypher is a bioscience company developing unique reagents and services for chromatin biology and epigenetics research.

A pioneer in the field of epigenetics and chromatin biology, EpiCypher is a bioscience company developing transformative technologies and delivering superior products to researchers world-wide. Our technologies and products are making studies possible that were not imaginable just a few years ago. Our innovation is a direct result of the scientific power associated with EpiCypher. Our renowned chromatin researchers possess expertise and unique insight into epigenetics that benefit our customers in ways other companies cannot. Arising from an abundance of demand for high quality products from the laboratories of Mark Bedford, Brian Strahl, and Or Gozani EpiCypher was founded on January 18, 2012 as a spin-out from University of North Carolina at Chapel Hill. Starting with the groundbreaking and proprietary histone peptide array platform, EpiGold™, EpiCypher has developed a wide portfolio of best in class products. EpiCypher's mission is to develop products to enable researchers to complete experiments that are not otherwise possible.

🧬 EpiCypher is heading to Montréal, Canada, for  , taking place October 20–24!📍 Stop by Booth  #416 to connect with our ...
10/14/2026

🧬 EpiCypher is heading to Montréal, Canada, for , taking place October 20–24!

📍 Stop by Booth #416 to connect with our team, and don't miss our poster presentations!

👩‍🔬Emily Madden, PhD, Product Manager, will present:

Long-read multiomic profiling of chromatin accessibility for antibody-free detection of protein footprints from cells and tissues

📅 Wednesday, October 21 | 2:30–4:30 PM EDT
📍 Poster Board

👨‍🔬Keith Maier, PhD, Associate Director, NGS Product Management, will present:

FFPE-CUT&Tag transcription profiling in patient biopsies reveals novel druggable pathways in lymphoma

📅 Thursday, October 22 | 4:15–6:15 PM EDT
📍 Poster Board

Whether you're interested in chromatin accessibility, long-read epigenomics, or FFPE-based profiling, we'd love to connect and discuss how our technologies can support your research!

đź’¬ Attending ? Let us know in the comments below.

🧬 EpiCypher is excited to be part of the New Investigators in Chromatin and Epigenetics (NICE) Conference 2026!📅 October...
10/12/2026

🧬 EpiCypher is excited to be part of the New Investigators in Chromatin and Epigenetics (NICE) Conference 2026!

📅 October 11–13, 2026
📍 Oklahoma Medical Research Foundation (OMRF) | Oklahoma City, OK

NICE 2026 brings together approximately 40 early-career investigators in chromatin and epigenetics to exchange innovative ideas, explore future research directions, and build meaningful scientific collaborations.

🎤 We're excited to have Sabrina R. Hunt, PhD, Research Scientist II at EpiCypher, presenting:

“Beyond ATAC-seq: Capturing Chromatin Accessibility at the Molecular Level — DAF-seq as a Platform for Single-Molecule Chromatin Accessibility Profiling”

We're looking forward to engaging discussions, new connections, and sharing insights into emerging approaches for studying chromatin accessibility at the single-molecule level!

🧬 EpiCypher is presenting at the 2026 EMGS Virtual Meeting! 👨‍🔬✨📅 October 12–14, 2026💻 Virtual EventJoin us for “Advanci...
10/09/2026

🧬 EpiCypher is presenting at the 2026 EMGS Virtual Meeting! 👨‍🔬✨

📅 October 12–14, 2026
đź’» Virtual Event

Join us for “Advancing Exposure Science: From Mechanisms to Risk,” bringing together researchers and industry experts to explore advances in genomics, epigenetics, DNA damage and repair, and environmental health.

Don't miss Keith Maier, PhD, EpiCypher's Associate Director of NGS Product Management, as he presents:

🔬Fiber-seq: Linking DNA Methylation to Chromatin Accessibility with Single-Molecule Long-Read Multiomics

đź”— Learn more: https://ow.ly/yEVC50ZWkkN

Now available: CUTANA™ ATAC-seq ServicesSend us your samples and let our chromatin mapping experts manage your ATAC-seq ...
10/08/2026

Now available: CUTANA™ ATAC-seq Services

Send us your samples and let our chromatin mapping experts manage your ATAC-seq project from experimental design through personalized data delivery.

We accept cryopreserved cells, isolated nuclei, and flash-frozen tissue. If your material requires upstream dissociation or nuclei extraction, our team can take that on.

Every project includes:
âś…A study design consult with our experts
âś…Upfront sample QC
✅ATAC-seq library preparation and sequencing using the same validated chemistry as our CUTANA™ ATAC-seq Kit
âś…Analysis-ready data, including raw sequencing reads, aligned reads, peak calls, and a detailed assay QC report
âś…A one-on-one review of your results with our scientists

Need a broader view of chromatin regulation? Add CUT&RUN, Fiber-seq and/or DNA Methylation Sequencing to the same project for multiomic profiling.

Ready to get started? Explore CUTANA™ ATAC-seq Services and tell us about your project:
https://ow.ly/jlzF50ZVrFi

Curious about Fiber-seq and what it can reveal about gene regulation? Join our webinar tomorrow (10/8 at 11 AM ET) hoste...
10/07/2026

Curious about Fiber-seq and what it can reveal about gene regulation? Join our webinar tomorrow (10/8 at 11 AM ET) hosted by The Scientist!

Our speaker, Dr. Ralph Grand, Group Leader at ZMBH, Heidelberg University, will share how his lab paired Fiber-seq with a degron system to rapidly remove specific transcription factors and isolate their individual roles in gene regulation.

Using Fiber-seq, his team was able to:
🧬Capture the gain and loss of transcription factor footprints
🧬Observe local shifts in nucleosome positioning
🧬Measure broader changes in chromatin accessibility across kilobase-scale regions

If you’re interested in understanding which factors are driving gene regulation, or how the presence or absence of a specific, potentially druggable factor reshapes regulation genome-wide, this webinar is for you!

Register here: https://ow.ly/pjaM50ZVzqk

Can’t attend live? Register anyway, and we’ll send the recording straight to your inbox!

NEW in the IDEA Toolbox: an exploratory dsDNA deaminase and its inhibitor, now commercially available.CUTANA™ SsDddA Dea...
10/06/2026

NEW in the IDEA Toolbox: an exploratory dsDNA deaminase and its inhibitor, now commercially available.

CUTANA™ SsDddA Deaminase and SsDddA Inhibitor (SsDddI) give researchers early access to the reagents behind two recently published single-molecule chromatin accessibility methods, DAF-seq and ACCESS-ATAC.

SsDddA converts accessible cytosine to uracil; SsDddI is its cognate inhibitor, used to quench deaminase activity. Together, they let you explore deaminase-based accessibility assays without expressing, purifying, and validating your own enzyme.

Explore the new IDEA Toolbox reagents: https://ow.ly/p3Yh50ZPk6Y

📢FIBER-SEQ PROMO! Save 15% on CUTANA™ Fiber-seq Kits and Hia5 Enzyme!Whether you're getting started with Fiber-seq or st...
10/01/2026

📢FIBER-SEQ PROMO!

Save 15% on CUTANA™ Fiber-seq Kits and Hia5 Enzyme!

Whether you're getting started with Fiber-seq or stocking up for upcoming experiments, take advantage of savings on:
🔹 CUTANA™ Fiber-seq Kits — 8 & 24 reactions
🔹 CUTANA™ Fiber-seq Hia5 Enzyme — 8 & 24 reactions

🏷️ Use code: FSEQ15 | Available to U.S. customers and through select distributors.
♾️ No limit on uses during the promotional period
đź“… Offer ends December 31, 2026

Order now: https://www.epicypher.com/products/fiber-seq/

How does our new CUTANA™ Tn5 Transposome perform head-to-head in ATAC-seq?In direct benchmarking at 50,000 and 10,000 K5...
09/30/2026

How does our new CUTANA™ Tn5 Transposome perform head-to-head in ATAC-seq?

In direct benchmarking at 50,000 and 10,000 K562 nuclei, CUTANA™ Tn5 Transposome matched a leading competitor enzyme for peak position and shape, TSS enrichment, and signal at shared peaks.

CUTANA™ Tn5 is pre-charged, ready to use, and compatible with Omni-ATAC workflows, giving researchers a flexible stand-alone enzyme option for chromatin accessibility profiling.

Want to benchmark it in your own lab? CUTANA™ Tn5 Transposome is available in multiple pack sizes, including a 25 µL format for $245, making it easy to start with a small-scale comparison before scaling up. Larger 125 µL and 625 µL formats are also available for higher-throughput workflows.

See all the data and explore CUTANA™ Tn5 Transposome ⤵️
https://www.epicypher.com/product/cutana-tn5-transposome/

Replay is now available! 🖥️Missed our latest PAG webinar? Watch the replay to learn how CUTANA™ Fiber-seq combined with ...
09/28/2026

Replay is now available! 🖥️

Missed our latest PAG webinar? Watch the replay to learn how CUTANA™ Fiber-seq combined with PacBio HiFi Sequencing enables highly accurate, long-read epigenomic profiling at the level of individual DNA molecules.

Hear from Christine Queitsch, PhD (University of Washington) and Rachel O’Neill, PhD (University of Connecticut) as they explore applications in plant and animal genomics, including:

- Connecting chromatin accessibility and nucleosome organization with underlying DNA sequence
- Investigating complex and repetitive genomes
- Exploring allele-specific regulation and regulatory variation
- Identifying opportunities across plant, agricultural, animal, and biodiversity research

🌟Watch webinar now: https://www.youtube.com/watch?v=YgZGGiaMky0

Curious about Fiber-seq and what it can reveal about gene regulation? Join our webinar hosted by The Scientist on 10/8.O...
09/25/2026

Curious about Fiber-seq and what it can reveal about gene regulation? Join our webinar hosted by The Scientist on 10/8.

Our speaker, Dr. Ralph Grand, Group Leader at ZMBH, Heidelberg University, will share how his lab paired Fiber-seq with a degron system to rapidly remove specific transcription factors and isolate their individual roles in gene regulation.

Using Fiber-seq, his team was able to:
- Capture the gain and loss of transcription factor footprints
- Observe local shifts in nucleosome positioning
- Measure broader changes in chromatin accessibility across kilobase-scale regions

If you’re interested in understanding which factors are driving gene regulation, or how the presence or absence of a specific, potentially druggable factor reshapes regulation genome-wide, this webinar is for you.

Register here: https://www.the-scientist.com/essential-genes-are-dominantly-activated-by-single-transcription-factors-74966

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6 Davis Drive
Durham, NC
27709

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