08/27/2024
Vascular geometry and perfusion status of vasculature surrounding tumors can impact drug delivery and efficacy. Create in vivo-like tumor heterogeneity and vascularization to test drug delivery, efficacy, metastasis and anti-cancer therapeutics with the SynTumor-on-Chip platform.
Key Features and Benefits:
1.Microvascular Networks: SynTumor-on-Chip incorporates realistic, perfusable vascular networks, which are crucial for mimicking the blood flow and nutrient supply in tumors. This feature allows for the study of drug delivery and distribution within a tumor, mirroring the in vivo conditions more closely.
2.3D Tumor Microenvironment: The platform supports the growth of tumor cells in a three-dimensional structure, which better replicates actual tumor architecture and cell-cell interactions found in the human body. This 3D environment is critical for understanding how tumors grow, invade surrounding tissues, and respond to therapies.
3. Real-Time Monitoring: The technology allows for continuous observation and analysis of tumor behavior and drug effects in real time. This capability provides dynamic insights into the mechanisms of drug action, resistance, and tumor progression.
4. Customizability: SynTumor-on-Chip can be tailored to model specific types of cancers, making it a versatile tool for research on different tumor types and for personalized medicine approaches. Researchers can recreate specific tumor microenvironments to study targeted therapies and personalized treatment strategies.
5.Reduced Animal Testing: By offering a more accurate representation of human tumors, SynTumor-on-Chip has the potential to reduce reliance on animal models in preclinical testing. This aligns both with the 3Rs mission and enhances the predictive power of preclinical studies.
Learn more and explore publications at www.synvivobio.com/syntumor.
