Syncell Inc

06/16/2026

What can we learn by mapping the proteins surrounding viral RNA during infection?
Join us for a virtual scientific event featuring Horacio Pallares, PhD from the Stowers Institute for Medical Research, who is applying spatial proteomics to investigate how flaviviruses such as dengue and Zika reorganize host cells to support replication and evade immune detection.

In his presentation, "Defining Flavivirus RNA Dynamics and Replication-Associated Host Factors by MICROSCOOP® Spatial Proteomics," Dr. Pallares will share how his team combines advanced RNA imaging with spatial proteomics to characterize the protein environments surrounding viral replication complexes and viral-induced RNA granules, providing new insight into host-pathogen interactions and viral biology at subcellular resolution.

This work highlights a powerful new approach for studying complex biological structures that have traditionally been difficult to isolate and analyze, opening new opportunities for discovery in virology, RNA biology, and infectious disease research.

You'll also hear from researchers at MD Anderson Cancer Center and VIB Tech Watch Core, who are using spatial proteomics to study cancer biology, cellular communication, and evaluate emerging research technologies.
Whether your work focuses on infectious disease, RNA biology, cell biology, proteomics, or technology development, this event offers a unique opportunity to explore how spatial proteomics is enabling previously inaccessible biological insights.

📅 June 26, 2026
⏰ 8:30 AM PT
🔗https://zoom.us/webinar/register/7717798758712/WN_B0eTWCs8S3OghJmfCTaIoA

06/09/2026

Millions of people are diagnosed with Alzheimer’s disease each year, with countless more impacted by its devastating effects. While there is still much work ahead, it’s important to recognize the scientists whose discoveries transformed our understanding of neurodegeneration and continue to shape the future of Alzheimer’s research.

🧠 Alois Alzheimer — First identified the plaques and tangles that transformed Alzheimer’s from a symptom of aging into a biological disease.

🧬 Rita Levi-Montalcini — Discovered nerve growth factor (NGF), laying the foundation for modern neurobiology and neurodegeneration research.

🔬 Stanley Prusiner — Revealed how misfolded proteins can drive disease, reshaping our understanding of neurodegeneration.

Scientific progress is built on the persistence and vision of those willing to see disease differently.

06/04/2026

Many subcellular structures are defined not only by molecular identity but also by their spatial organization, morphology, and cellular context. As reviewed in a recent Molecular & Cellular Proteomics article, conventional proximity labeling methods typically rely on genetic fusion or antibody-mediated targeting of labeling enzymes, which can limit analysis to predefined molecular targets.

To address this challenge, the review highlights microscopy-guided subcellular proteomics (optoproteomics), which combines fluorescence imaging with targeted photolabeling of proteins within visually selected subcellular regions. By enabling proteomic profiling based on spatial features and morphology, this approach can characterize structures such as stress granules and amyloid-β plaques with high spatial specificity and sensitivity.

https://www.sciencedirect.com/science/article/pii/S1535947626000150

06/02/2026

Announcing Syncell’s first-ever Virtual User Group Meeting to be held on June 26! This event brings together top-tier scientists applying Microscoop across a variety of research areas.

Join us for scientific presentations followed by a live panel Q&A with featured users from leading research institutions: Jared K. Burks at MD Anderson, Horacio Martín Pallarés at Stowers Institute for Medical Research and Bram Van den Bergh at VIB Tech Watch Core.

https://zoom.us/webinar/register/7717798758712/WN_B0eTWCs8S3OghJmfCTaIoA

📅 June 26, 2026. 8:30am - 10:30am PT
🎤 15-minute presentations + live panel Q&A
🌍 Virtual event

06/01/2026

In honor of Alzheimers disease awareness month, we’ll spend the next several weeks exploring the biology of this condition, and the history of ongoing progress to understand it.
In our latest blog, we explore how spatial proteomics is helping researchers understand not just what changes in neurodegenerative disease, but where those changes occur within the intricate architecture of the brain.
Many of the molecular events involved in neurodegeneration unfold within highly localized cellular environments — at synapses, mitochondria, stress granules, and neuroimmune interfaces — yet much of this biology remains difficult to capture using conventional bulk approaches.
As neuroscience increasingly moves toward systems-level and spatially resolved biology, researchers are gaining new ways to investigate disease directly within its native cellular context.

▶️ Read the blog to learn more: https://www.syncell.com/blog/beyond-plaques-and-tangles-how-spatial-proteomics-could-unlock-the-next-era-of-alzheimers-research/

05/29/2026

Meet us at the Bruker eXceed Symposium at ASMS; we'll be exhibiting at booth 14. Register today to hear inspiring talks and chat with us!
https://www.bruker.com/en/landingpages/bdal/asms.html
📅 Sunday, May 31. 8:30am PT
📍Manchester Grand Hyatt San Diego

Join Bruker at ASMS 2026. Meet us in San Diego from May 31 - June 4 for breakthrough technologies, inspiring science, and hands‑on conversations with our experts.

05/28/2026

We’re excited to announce the commercial launch of Syncell Discovery Services — a new global sample-to-discovery program providing researchers direct access to unbiased nanoscopic spatial proteomics powered by the Microscoop® Mint platform.
As demand grows for higher-resolution approaches in biomarker discovery, drug target identification, and disease biology research, Syncell Discovery Services enables biopharma, translational research groups, and academic labs to submit samples directly for in situ proteomic profiling with subcellular spatial precision.
From oncology and neuroscience to immunology and cell biology, researchers can now uncover proteins and spatial biology insights that are often inaccessible through conventional spatial proteomics workflows.
"This unbiased spatial optoproteomics approach allowed us, for the first time, to identify candidates in the protein adhesion complex at the whole proteome level, which we are now functionally validating as potential drug targets for cancer," said William Hwang, M.D, Ph.D., at Massachusetts General Hospital and Assistant Professor, Harvard Medical School.

Learn how Syncell Discovery Services can accelerate your discovery pipeline and unlock new therapeutic insights:
https://www.syncell.com/news-center/news/syncell-launches-high-precision-proteomics-discovery-service-powered-by-microscoop-mint-platform/

05/27/2026

Protein aggregates are one of the defining hallmarks of neurodegenerative disease — but what’s inside those aggregates remains largely unexplored.
Bulk proteomics often misses the rare, spatially localized proteins that may drive disease progression in Alzheimer’s, Parkinson’s, ALS, Huntington’s disease, and FTD.
With microscopy-guided subcellular proteomics, researchers can now selectively profile proteins from aggregate-associated regions and their surrounding microenvironments with exceptional spatial precision.

05/25/2026

In a Nucleus conference review on emerging technologies for studying nuclear substructures, Microscoop is described as a “turnkey system for proximity labeling” that uses a photoactivatable biotin compound for “high-content in situ photolabeling.” The authors highlight its ability to “train” the photoactivation beam microscopically, enabling labeling confined to a delimited nuclear site and supporting spatially precise proteomic interrogation of nuclear microenvironments.

https://www.tandfonline.com/doi/full/10.1080/19491034.2024.2404677

05/22/2026

Excited to be heading to in San Diego!
We’ll be showcasing how Microscoop® enables spatially resolved proteomics through microscopy-guided photolabeling prior to LC-MS/MS — preserving native biological context.

📍 Booth #916
📌 Poster Presentation — June 2 | 10:30 AM

Looking forward to connecting and talking surfaceome characterization, organelle proteomics, and FFPE workflows. See you there!