09/02/2026
New Publication Alert:
Proteomic subtyping of brain region-specific astrocytes was achieved by microscopy-guided regional photo-biotinylation and mass spec analysis using Microscoop®. Paraformaldehyde-fixed, OCT-embedded mouse brain tissue was used and astrocytes of hippocampal and cerebral cortical regions were separately isolated to identify region-specific proteomes. Novel candidate markers, MINK1 and PLEKHB1, showed preferential expression in hippocampal and cortical astrocytes, respectively.
https://pubs.acs.org/doi/10.1021/acs.jproteome.6c00321