08/27/2026
Diseases like frontotemporal dementia begin long before symptoms appear. But until now, researchers did not have a good way to watch those first moments happen in human neurons.
A new Science Advances study describes lab-grown neurons that develop tau pathology on their own, in the right order, and report their tau levels as a simple luminescent light signal. That combination makes it practical to screen for drugs that could stop the damage early.
Lab-grown neurons that develop tau pathology naturally and emit light signals offer a new model for drug screening.