05/29/2026
Accurate fibrosis assessment is critical in MASLD — especially for patients with type 2 diabetes, where advanced fibrosis may remain under-identified.
At ADA 2026, Fibronostics will present clinical evidence showing that LIVERFASt™ outperformed FIB-4 for identifying ≥F3 fibrosis in patients with MASLD, including those with T2D.
In the overall MASLD population, LIVERFASt™ showed 66% sensitivity vs 36% for FIB-4 at the high-risk cut-off, with 72% PPV and 74% NPV. In patients with T2D, LIVERFASt™ showed 67% sensitivity vs 30% for FIB-4, supporting stronger identification in a high-risk population.
When used before VCTE in a sequential pathway, LIVERFASt™ also reduced unnecessary VCTE referrals and generated 20% more correctly classified patients compared with the recommended FIB-4 pathway.
More insights coming to ADA 2026.