We offer you an ever expanding array of high quality, cost-effective products for your research and development. AnamChem is located in San Diego, California, a city that ranks #7 as a global biotech cluster, and is the home of several of the top universities in the world, University of California, San Diego (UCSD), University San Diego (USD), and San Diego State University (SDSU). Research scient
ists like us would like to stretch their budget to accomplish more research milestones. AnamChem was founded in 2012, by Sang Van, Ph.D., with the mission of delivering more value to your research budget. AnamChem was founded for the purpose of developing and commercializing an extensive line of very cost-effective products for companies involved in drug delivery, drug discovery, and diagnostic development programs. These products are produced based on our proprietary manufacturing processes and chemistry. This approach is exemplified in some of our products, mono-Boc-protected diamines which are very useful building blocks for chemical synthesis. However, production of mono-Boc-protected diamines with a good yield is very challenging. For instance, a reaction of ethylene diamine and Boc-anhydride reagent can produce mono-Boc protected ethylene diamine but also can produce a mixture of unprotected ethylene diamine and di-boc protected ethylene diamine (as shown below) because the ethylene diamine cannot differentiate between the two identical amino moieties in the substrate. By controlling concentration of ethylene diamine, ratio of diamine to Boc-anhydride, temperature of a reaction, and improving work-up processes, the maximum yield of the reaction under optimal conditions is above 50%. Using similar conditions and processes, our product lines are expanding to other diamines such as propanediamine, hexanediamine, PEG2-diamine, and PEG3-diamine. Other feature products are based on our proprietary N-Boc-dendramine chemistries (patent application no. 61/694,200), including our robust processes for making these important compounds. N-Boc-dendramine (as shown below), can be a complement to dendrimer technology in terms of development of therapeutic and diagnostic products with more precision and control. We will also be involved in developing new cross-linking, labeling chemistry, and incorporating targeting ligands and imaging agents onto the mono-Boc protected diamine technology and mono-Boc protected dendramine technology. The incorporation will allow research scientists to explore completely new approaches to existing opportunities in these same areas of targeting, therapeutic, and diagnostic development. It will be an exciting field! People
Sang Van, Ph.D. Chief Executive Officer
In 2002, Dr. Sang Van received a Ph.D. degree in Chemistry from a joint doctorate program at University of California, San Diego and San Diego State University, and joined Nitto Denko Technical Corporation as a research scientist to explore polymer technologies for gene/siRNA and drug delivery and bio-medical uses. He has extensive knowledge and experience in the bio-medical field, including drug carrier technology and drug delivery patents and/or applications. He has been awarded with eleven U.S. patents for drug and biological molecule delivery, and he is also a co-inventor of fifteen published U.S. patent applications related to drug and biological molecule delivery. He is named as an author on numerous publications regarding drug carrier technology, including publications related to polymer drug delivery and polymer gene/siRNA delivery. Beltran Rodriguez-Mueller (nee Rodriguez-Brito), Ph.D. Director of Operations
In 2010, Beltran Rodriguez-Mueller received his Ph.D. from the Claremont Graduate University/San Diego State University Joint Doctoral Program in Computational Sciences. He joined Anamchem after finishing his postdoctoral work at the San Diego State branch of NIH’s Human Microbiome Project. His work is reflected in 25+ peer-reviewed papers, including four papers in Nature. The high impact of this work is reflected by the more than 2000 citations accumulated. He joins Anamchem bringing a depth and breath of experience in the confluence of mathematical analysis and modeling, biology, and data analysis.
