The Krogan Lab

01/03/2022

Nevan Krogan was featured on Korean news podcast TBS eFM This Morning, discussing the implications of new research into commonalities between the variants and the importance of vaccinations

Listen here: https://podcasts.apple.com/kr/podcast/tbs-efm-this-morning/id1038822609

tbs eFM [101.3 MHZ] is a 24 hour foreign language radio operating from Seoul, Korea. Our diverse programs cover the areas of news, current affairs, music, cu...

01/03/2022

“San Francisco is really the epicenter of SARS-COV-2 research,” said Nevan Krogan, director of QBI at UCSF. “Many people in the Bay Area may not realize how much we are quarterbacking this.”

‘Many people in the Bay Area may not realize how much we are quarterbacking this’

06/16/2021

The pandemic and political tensions might slow the march towards more globalized science.

06/07/2021

Scientists from QBI UCSF, University College London and QCRG published a new study describing how specific mutations of the B.1.1.7 U.K. coronavirus strain i...

06/07/2021

Emergence of SARS-CoV-2 variants, including the globally successful B.1.1.7 lineage, suggests viral adaptations to host selective pressures resulting in more efficient transmission. Although much effort has focused on Spike adaptation for viral entry and adaptive immune escape, B.1.1.7 mutations out...

03/29/2021

Action for Ally, led by Betsy Jung Trainor, will be hosting a with
Rare Revolution Magazine tomorrow to spread awareness about a rare progressive neurodegenerative disease called . Tune in to learn about their fight against the disease in partnership with The Krogan Lab!

http://actionforally.com

03/29/2021

Action for Ally has partnered with the Krogan Lab to begin research on the pathogenic gene that causes ARSACS. It is our hope that this fundamental research will be a launching pad for potential avenues of treatment and/or one day a cure.

Tune in to their tomorrow with Rare Revolution Magazine to learn more.

03/01/2021

After cardiovascular injury, numerous pathological processes adversely impact the homeostatic function of cardiomyocyte, macrophage, fibroblast, endot…

02/19/2021

There are multiple COVID-19 variants circulating the Bay Area, making it harder for this pandemic to be under control. Here's what UCSF scientists are trying to do to figure out the best drugs to kill them.

02/05/2021

We reported in Science the potent antiviral efficacy of Plitidepsin (Aplidin) against . In a parallel study posted on , we found it to retain its antiviral efficacy against the UK B.1.1.7. variant in Caco-2 (left) and Calu-3 (right) cells

Read More Here: https://www.biorxiv.org/content/10.1101/2021.01.24.427991v1?rss=1

02/03/2021

SARS-CoV-2 viral proteins interact with the eukaryotic translation machinery and inhibitors of translation have potent antiviral effects. Here we report that the drug plitidepsin (aplidin), which has limited clinical approval, possesses antiviral activity (IC90 = 0.88 nM) 27.5-fold more potent than....

12/29/2020

Check out this article from Elemental about the research done by Nevan Krogan's team on how "antidepressants and antipsychotics could offer protection against the coronavirus."

Antidepressants and antipsychotics could offer protection against the coronavirus, but not because of their effect on the brain