Pliant Therapeutics

Pliant Therapeutics Pliant Therapeutics is a clinical-stage biotechnology company focused on the discovery and development of integrin-based therapeutics.

Excited to present FORTIFY, our ongoing Phase 1b trial, to the global oncology community at the 2026 American Society of...
05/21/2026

Excited to present FORTIFY, our ongoing Phase 1b trial, to the global oncology community at the 2026 American Society of Clinical Oncology (ASCO) Annual Meeting. FORTIFY is an indication expansion trial investigating PLN-101095 in combination with pembrolizumab that is enrolling patients with certain immune checkpoint inhibitor (ICI)-refractory advanced or metastatic solid tumors. Presentation details: https://lnkd.in/gm2jwWqF

Excited to announce the dosing of the first patient in our FORTIFY Phase 1b indication expansion trial. This trial is ev...
04/30/2026

Excited to announce the dosing of the first patient in our FORTIFY Phase 1b indication expansion trial. This trial is evaluating PLN-101095, our novel dual integrin inhibitor, in combination with pembrolizumab in patients with immune checkpoint inhibitor (ICI)-refractory solid tumors.

While ICIs have transformed cancer care, approximately 70–85% of patients with solid tumors do not respond to or develop resistance to them. Read more about FORTIFY, today’s news and how Pliant is focused on addressing underserved areas of medical need: https://ir.pliantrx.com/news-releases/news-release-details/pliant-therapeutics-announces-first-patient-dosed-fortify-phase

In an oral presentation today, UT MD Anderson Cancer Center's Dr. Timothy Yap presented updated results from our Phase 1...
04/18/2026

In an oral presentation today, UT MD Anderson Cancer Center's Dr. Timothy Yap presented updated results from our Phase 1 trial of PLN-101095 in patients with ICI-refractory solid tumors as part of the American Association for Cancer Research's 2026 Annual Meeting. Review the data and presentation https://lnkd.in/gCvrb5fQ

Today we announced our Fourth Quarter 2025 Financial Results and provided a company update. Review the press release her...
03/11/2026

Today we announced our Fourth Quarter 2025 Financial Results and provided a company update. Review the press release here: https://lnkd.in/g23DEQ-R

Today we announced encouraging interim data from our Phase 1 trial of PLN-101095 in patients with immune checkpoint inhi...
12/04/2025

Today we announced encouraging interim data from our Phase 1 trial of PLN-101095 in patients with immune checkpoint inhibitor-refractory advanced or metastatic solid tumors.

We welcome you to review the press release https://lnkd.in/gZqX99PC and listen to our senior leadership discuss these data today at 12:30 pm ET as part of a Piper Sandler fireside chat: https://lnkd.in/gep-MAFx.

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331 Oyster Point Boulevard
South San Francisco, CA
94080

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