INDIGO Biosciences, Inc

09/07/2026

In observance of Labor Day, INDIGO Biosciences will be closed on Monday, September 7. We will resume normal business hours on Tuesday, September 8. Wishing everyone a safe and relaxing holiday weekend!

09/04/2026

A predefined screening panel may not reflect the targets or questions most relevant to your drug discovery program.

INDIGO’s Nuclear Hormone Receptor (NHR) Panel Screening service provides the flexibility to build a study around your compounds and research objectives. From focused screening against selected receptors to broader functional profiling, your panel can be tailored to generate the data your team needs.

Customized NHR panels can help you:
🧬 Compare functional activity across receptors
🧩 Investigate compound selectivity
🎯 Identify activity at related targets
💊 Prioritize compounds for additional characterization

Start with your compounds and research question. We’ll help you build the panel to answer it. https://bit.ly/4r0vozx

09/02/2026

Rediscover INDIGO's Retinoid X Receptor (RXR) Assays!

Retinoid X Receptors (RXRα, RXRβ, and RXRγ) are ligand-activated nuclear receptors that regulate gene expression through heterodimerization with other nuclear receptors, including PPARs, LXRs, FXR, and VDR. Because of their role in coordinating metabolic, developmental, and endocrine signaling, RXRs are widely studied in metabolic disease, oncology, inflammation, dermatology, and other areas of translational research.

The principal application of this reporter assay system is in the screening of test samples to quantify functional activity they may exert against the RXRs.

Talk to one of our scientists today about our human RXR assays! https://bit.ly/3UrpF9T

09/01/2026

A recent publication titled "Metabolic activation of lumisterol to biologically active metabolites and their mechanism of action" utilized INDIGO's AhR assay!

"These findings open previously unexpected, exciting new areas of research on the physiological role of lumisterols through their action on defined nuclear receptors."

Read now by clicking on the link below 🎉

https://bit.ly/4xlOrpL

08/28/2026

You do not need to have every element of your Receptor Panel determined before contacting INDIGO. Start with your compound and research question!

Our scientists can help select:
🧬 Relevant receptors
👩‍🔬 Activation, inhibition, or both testing modes
🧪 Appropriate concentrations and controls
🔬 Options for comparing and prioritizing compounds

Following testing, clients receive a complete data package and study report to support interpretation and next-step planning. Tell us about your compound and research objective, and we’ll help recommend an appropriate screening approach.

Full Portfolio Receptor Profiling Services At INDIGO Biosciences, we provide an extensive suite of Receptor Profiling services, offering detailed insights into compound interactions across key receptor families. Our Full Panel Screens for Nuclear Receptors (NRs), G Protein-Coupled Receptors (GPCRs),...

08/27/2026

The INDIGO Team had a fantastic time in San Francisco for the WateReuse California Conference. Thank you so much to everyone who stopped by the table to chat bioassays for water reuse!

08/26/2026

Rediscover INDIGO's Vitamin D Receptor (VDR) Assays!

The Vitamin D Receptor (VDR) is a ligand-activated nuclear receptor that regulates calcium and phosphate homeostasis, bone metabolism, immune function, and cellular differentiation. Because of its broad physiological role, VDR is widely studied in osteoporosis, kidney disease, immune and inflammatory disorders, and other areas of metabolic and endocrine research.

The principal application of this reporter assay system is in the screening of test samples to quantify functional activity they may exert against VDR.

Talk to one of our scientists today about our human VDR assays! https://hubs.la/Q04vlP9y0

08/21/2026

Explore Functional Effects Across Related Targets

Binding or structural information can indicate that a compound interacts with a receptor, but it may not show whether the compound activates or inhibits receptor activity. Functional testing provides a direct measurement of receptor response. Across a panel of growth factor receptors, these data can help teams:

🧪 Compare activation or inhibition across targets
🔬 Differentiate compounds with similar binding profiles
🧬 Evaluate functional activity at related receptors
💊 Prioritize candidates for additional testing

INDIGO’s cell-based growth factor receptor assays can be combined into customized panels based on the targets most relevant to your program. Talk to a scientist about tour project today! https://hubs.ly/Q04tVm9G0

08/19/2026

Rediscover INDIGO's Farnesoid X Receptor (FXR) Assays!

The Farnesoid X Receptor (FXR) is a ligand-activated nuclear receptor that regulates bile acid homeostasis, lipid and glucose metabolism, and inflammatory responses. Because of its central role in hepatic and metabolic function, FXR is widely studied in liver disease, cholestatic disorders, metabolic dysfunction-associated steatohepatitis (MASH), and broader cardiometabolic research.

The principal application of this reporter assay system is in the screening of test samples to quantify functional activity they may exert against FXR.

Talk to one of our scientists today about our human FXR assays! https://hubs.la/Q04twNwk0

08/17/2026

A recent publication titled "Ultraviolet radiation reshapes the metabolome of skin commensal bacteria, influencing AhR signaling and barrier function" utilized INDIGO's AhR assay!

"UVR significantly alters the metabolomes of skin commensal bacteria, with knock-on effects for AhR signaling and barrier integrity, potentially influencing the skin’s response to UVR."

Read now by clicking on the link below 🎉

https://hubs.la/Q04tdkmz0