INDIGO Biosciences, Inc

11/05/2026

A recent publication titled "Individual variation in estrogenic plant consumption predicts f***l estradiol levels in the Ugandan red colobus monkey (Piliocolobus tephrosceles)" utilized INDIGO's ERβ assay!

"To test whether daily variation in wild estrogenic plant consumption was associated with subsequent variation in f***l steroid hormone concentrations, we sequentially followed six individually recognized Ugandan red colobus monkeys (Piliocolobus tephrosceles) in Kibale National Park, Uganda, over an eight-month study period, collecting 1318 h of behavioral observations and 516 f***l samples."

Read now by clicking on the link below 🎉

https://bit.ly/3UAgFPV

11/04/2026

Rediscover INDIGO's Estrogen-Related Receptor Alpha (ERR) Assays!

The Estrogen-Related Receptor (ERR) family includes ERRα, ERRβ, and ERRγ, three orphan nuclear receptors that regulate transcriptional programs involved in mitochondrial function, oxidative metabolism, and energy homeostasis. Although structurally related to estrogen receptors, ERRs do not bind estrogen and are studied across metabolic disease, cardiovascular biology, muscle function, neurodegeneration, and oncology.

The principal application of this reporter assay system is in the screening of test samples to quantify functional activity they may exert against ERR.

Talk to one of our scientists today about our ERR assays! https://bit.ly/4A2Cvus

11/02/2026

Contact us today to take advantage of this limited time offer and get 20% off compound screening services of more than $10,000 until November 20th!* https://bit.ly/4zqgupK

10/30/2026

Rediscover INDIGO's Pregnane X Receptor (PXR) Assays!

The Pregnane X Receptor (PXR) is a ligand-activated nuclear receptor that acts as a key xenobiotic sensor, regulating genes involved in drug metabolism and transport. Because PXR activation can influence CYP enzyme expression, drug disposition, and drug-drug interaction potential, it is widely studied in ADME, toxicology, DDI, and safety assessment programs.

The principal application of this reporter assay system is in the screening of test samples to quantify functional activity they may exert against PXR.

Talk to one of our scientists today about our PXR assays! https://hubs.la/Q04CSjVp0

10/28/2026

Every compound and development program has a different set of endocrine safety questions.

INDIGO scientists work collaboratively with research teams to configure Endocrine Safety Screening studies around program-specific objectives. You can begin with a focused panel of estrogen, androgen, and thyroid hormone receptors, or discuss expanded coverage when your program calls for it.

Our scientists can help determine which receptors should be included, which assay formats best address your research question, and how the resulting data can support follow-up testing.

From initial screening through more targeted investigation, INDIGO can tailor an endocrine profiling strategy to fit your compound, development stage, and safety objectives.

Endocrine disruptor testing using human-relevant, functional nuclear receptor assays to identify hormone-mediated safety risk early.

10/26/2026

With an extensive portfolio of cell-based reporter assays including Nuclear Receptors, GPCRs, Growth Factors, and more, INDIGO Biosciences' highly qualified technical support team is dedicated to helping you accelerate your scientific decision making.

We also want to provide you with cost-effective solutions. So, for a limited time, we're offering 20% off compound screening services of more than $10,000 until November 20th* to help you get the data you need, while helping your budget go farther. Contact us today! https://hubs.la/Q04C3YLf0

10/23/2026

Rediscover INDIGO's Aryl Hydrocarbon Receptor (AhR) Assays!

The Aryl Hydrocarbon Receptor (AhR) is a ligand-activated transcription factor that responds to a wide range of endogenous and environmental compounds and regulates genes involved in xenobiotic metabolism, immune function, barrier biology, and cellular differentiation. Because of its broad biological role, AhR is widely studied in toxicology, inflammation, immunology, oncology, and environmental health research.

The principal application of this reporter assay system is in the screening of test samples to quantify functional activity they may exert against AhR.

Talk to one of our scientists today about our AhR assays! https://hubs.la/Q04C32Dq0

10/22/2026

🚨Serotonin Assay Now Available!🚨
We're excited to announce the latest addition to our assay catalog: the Human 5-Hydroxytryptamine Receptor 2A (5-HT2A)!

This new assay equips researchers with a toolkit to characterize 5-HT2A activity, accelerating the development of therapeutics for physiological processes, including cognition, mood, sensory perception, nociception, gastrointestinal function, cardiovascular regulation, and sleep.

Our assay kits provide researchers with an all-inclusive luciferase reporter system that includes pre-transfected reporter cells, optimized media for use during cell culture and in diluting the user’s test samples, a reference compound, luciferase detection reagent, and a cell culture-ready assay plate. INDIGO Biosciences can also perform the 5-HT2A assays in our lab as a service for researchers! https://hubs.la/Q04C12Tj0

10/21/2026

A screening result becomes more useful when you can see which receptor responded, how the response changed with concentration, and how compounds compare.

INDIGO’s functional endocrine profiling generates concentration-response relationships, potency measurements, and receptor-specific activity profiles that can support interpretation beyond a simple positive or negative result. Teams can use this data to compare compounds in a series, investigate an unexpected result, and decide which findings need further characterization.

Explore our Endocrine Screening options now!

Endocrine disruptor testing using human-relevant, functional nuclear receptor assays to identify hormone-mediated safety risk early.

10/19/2026

Contact us today to take advantage of this limited time offer and get 20% off screening services of more than $10,000 until November 20!*

https://hubs.la/Q04BzxJv0