INDIGO Biosciences, Inc

INDIGO Biosciences, Inc Bring the power of INDIGO to your lab with convenient lab-in-a box Nuclear Receptor Assay Kits. Or put our experts to the test with Contract Screening.

INDIGO Biosciences, Inc. was founded in 2005 in State College, PA. It remains a privately held biosciences company offering products and services focused on nuclear receptors, which comprise a major class of therapeutic drug targets. The Company's two founders, Dr. Jack Vanden Heuvel and Dr. Blake Peterson, leveraged their collective expertise's in nuclear receptor biology, toxicology, medicinal c

hemistry and molecular biology to establish the core platform technology of The Company. INDIGO Biosciences' original focus was that of a traditional contract research organization, namely, to provide custom services for the screening of small molecule compounds against functional human and non-human nuclear receptors. Over the years, The Company has demonstrated success in providing quality screening services to clients within the pharmaceutical, biotechnology, food, agriculture and nutriceutical industries, government research agencies, as well as to academic researchers.

Bioassays can detect the biological effects of targeted, non-targeted, and even unknown contaminants, providing a compre...
06/09/2026

Bioassays can detect the biological effects of targeted, non-targeted, and even unknown contaminants, providing a comprehensive assessment of water quality and highlighting the presence of potential risks before they become significant hazards.

Utilizing bioassays as another pillar of water quality monitoring ensures that water intended for reuse is thoroughly evaluated and safe, protecting both human health and the environment.

Learn more on our website! https://bit.ly/49OTTIL

Close the Gap Between Animal Models and Human OutcomesWe offer more than 50 alternate species receptor assays across com...
06/05/2026

Close the Gap Between Animal Models and Human Outcomes
We offer more than 50 alternate species receptor assays across commonly used laboratory species, including rat, mouse, dog, monkey, pig, and rabbit. These assays can help researchers compare receptor activity across species and improve confidence in study design and downstream interpretation.

Learn More About INDIGO’s Alternative Species Profiling Services on our Website! https://bit.ly/3RGLfG2

Rediscover INDIGO's Fibroblast Growth Factor Receptor Assay Family! The FGFR family regulate cell growth, differentiatio...
06/03/2026

Rediscover INDIGO's Fibroblast Growth Factor Receptor Assay Family!

The FGFR family regulate cell growth, differentiation, survival, and tissue repair. Because of their roles in development and disease, FGFRs are widely studied in oncology, fibrosis, skeletal disorders, metabolic disease, and regenerative medicine.

Ready to rediscover what our FGFR assays can reveal in your program? Talk to one of our scientists today! https://bit.ly/43NuGL8

Our assay uses upcyte® hepatocytes, which retain liver-specific functions such as:CYP450 enzyme activityDrug transporter...
06/02/2026

Our assay uses upcyte® hepatocytes, which retain liver-specific functions such as:

CYP450 enzyme activity
Drug transporter expression
Albumin production

Unlike immortalized cancer derived cell lines (http://e.g., HepG2), upcyte® hepatocytes are derived from healthy human liver tissue and retain more physiologically relevant functions, offering greater predictive power for assessing liver toxicity.

https://bit.ly/4dZLpQ4

If your team needs to evaluate GR-mediated repression of NF-κB signaling, INDIGO can help design a study around the ques...
05/29/2026

If your team needs to evaluate GR-mediated repression of NF-κB signaling, INDIGO can help design a study around the question that matters most.

Our scientists work with clients to develop GR/NF-κB transrepression assay strategies that align with the compound, mechanism, and stage of research. Whether the goal is early screening, compound comparison, or deeper pathway characterization, INDIGO can help define an assay approach that fits your program.

Connect with an INDIGO scientist and design your study now! https://hubs.ly/Q04hXz-p0

This recent publication titled "Assessment of chemical extracts of urban air for endocrine disruption using a serie of i...
05/28/2026

This recent publication titled "Assessment of chemical extracts of urban air for endocrine disruption using a serie of in vitro bioassays: a case study in Montreal, Canada" utilized INDIGO's AR and ERα assay kit!

"Overall, our data indicate the potential for thyroid, estrogenic, antiestrogenic and antiandrogenic disruption caused by the chemical mixtures present in the outdoor air of a major metropolis. This work provides one of the first integrated assessments of endocrine activity from atmospheric vapour phase chemical extracts, underscoring the importance of incorporating bioanalytical tools into air-quality and health-risk evaluation frameworks."

Read now by clicking on the link below 🎉

https://hubs.la/Q04hXG-l0

Rediscover INDIGO's Gastric Inhibitory Polypeptide Receptor (GIPR) Assays!GIPR is a class B G protein-coupled receptor t...
05/27/2026

Rediscover INDIGO's Gastric Inhibitory Polypeptide Receptor (GIPR) Assays!
GIPR is a class B G protein-coupled receptor that mediates the activity of glucose-dependent insulinotropic polypeptide and plays an important role in insulin secretion, energy balance, and metabolic regulation.

Because of its relevance in glucose homeostasis and body weight control, GIPR is widely studied in obesity, type 2 diabetes, and cardiometabolic research.

The principal application of this reporter assay system is in the screening of test samples to quantify functional activity they may exert against GIPR. Talk to one of our scientists today about our human GIPR assays! https://hubs.la/Q04hXNTH0

05/25/2026

In observance of Memorial Day, INDIGO Biosciences is closed. Today, we honor and remember the brave men and women who gave their lives in service to our country.

We will be back in the office on Tuesday, May 26th.

INDIGO’s GR/NF-κB Transrepression Assay can help researchers assess whether a compound influences GR-mediated repression...
05/22/2026

INDIGO’s GR/NF-κB Transrepression Assay can help researchers assess whether a compound influences GR-mediated repression of inflammatory signaling, generating functional data that may support ranking, differentiation, and follow-up study design.

Depending on program needs, this type of study may help teams:
🧠 Compare GR-active compounds using a transrepression endpoint
🧬 Investigate mechanism in inflammation-focused programs
🧪 Support screening of selective modulators
🔬 Add functional context to broader receptor pharmacology packages

Because the assay is designed around a biologically relevant signaling question, the resulting data can help researchers interpret compound behavior with greater confidence.

See how transrepression data can support your program! https://hubs.la/Q04hjxLN0

We recently added GPR39 to our assay portfolio, giving researchers a precise and reliable way to characterize GPR39 acti...
05/21/2026

We recently added GPR39 to our assay portfolio, giving researchers a precise and reliable way to characterize GPR39 activators and inhibitors with high reproducibility and minimal lot-to-lot variability.

Find this reporter assay and more on our website! https://hubs.la/Q04ht2mG0

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3006 Research Drive, Suite A1
State College, PA
16801

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Monday 8am - 5pm
Tuesday 8am - 5pm
Wednesday 8am - 5pm
Thursday 8am - 5pm
Friday 8am - 5pm

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