08/31/2026
In 1937, a medicine that tasted like raspberry cordial killed 105 Americans β and the government could only seize it over a spelling error. π§ͺ
The drug itself (sulfanilamide) worked fine. The killer was the solvent: diethylene glycol β sweet, syrupy, cheap, and lethal. No law required safety testing, so nobody tested it. The label said "elixir," which legally implies alcohol β and that misbranding technicality was the ONLY authority the FDA had to pull it off shelves.
What happened next:
1οΈβ£ 239 FDA inspectors chased 240 gallons across 633 shipments β and recovered all but ~6 gallons
2οΈβ£ Those 6 gallons killed 105 people, 34 of them children
3οΈβ£ The company's total fine: $26,100 β about $250 per death
4οΈβ£ Congress passed the 1938 Food, Drug & Cosmetic Act β the law that created the modern FDA
Here's the part that isn't history: propylene glycol (the safe glycol that replaced DEG) and diethylene glycol still look, pour and taste identical. The same substitution killed 300+ children in cough syrups in 2022β23. Only laboratory analysis tells them apart β which is why U.S. rules now require identity testing of every single container.
We supply propylene glycol in USP Grade, Technical Grade and Inhibited (heat-transfer) form β certificate of analysis tied to your actual lot, in the box, every order. Not sure which grade your process needs? Tell us the application and we'll spec it.
Full story: https://alliancechemical.com/blogs/articles/elixir-sulfanilamide-1937-diethylene-glycol-disaster-fda
Save this for the next person who says "the label says it's fine."