Creative Diagnostics

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Creative Diagnostics

Creative Diagnostics is a leading manufacturer and supplier of antibodies, viral antigens, innovative diagnostic components and critical assay reagents.

We also assist clients in rapidly developing, manufacturing and commercializing point of care lateral flow, flow through and ELISA assays for any market segment. We develop using fluorescent, visual colloidal gold and paramagnetic labels,and high sensitivity, quantitative and reader-based tests are our specialty. With the decades of experiences and our unique technologies, Creative Diagnostics prides itself on its commitment to providing its customers in research and industry the highest quality products and services.

28/10/2026

Neurons communicate across a tiny gap called the synaptic cleft, and trans-synaptic adhesion molecules like Neuroligins and Neurexins are the "handshake" that holds both sides together. These molecules guide synapse formation, maintenance, and plasticity, and are linked to Alzheimer's, schizophrenia, and Down syndrome.

Creative Diagnostics offers a focused collection of Synaptic Adhesion Antibodies for neuroscience research.

✔ Targets: LRRTM1, LRRTM3, NCAM1/CD56, NCAM2, Neuroligin 1, Protocadherin-1, SynCAM 1
✔ Monoclonal and polyclonal formats, incl. phospho-specific options
✔ Applications: WB, IHC-P, ICC/IF, IP, FC, ELISA
✔ Human, mouse, and rat reactivity

Learn more: https://www.creative-diagnostics.com/synaptic-adhesion.htm

23/10/2026

Neural stem cells (NSCs) play important roles in nervous system development, plasticity, aging, disease, and regeneration.

Reliable marker antibodies are essential for identifying NSCs and studying the molecular pathways that regulate their self-renewal, differentiation, and cell fate.

Creative Diagnostics provides Neural Stem Cell Marker Antibodies targeting key markers including:

• Nestin
• SOX2
• E-cadherin / CDH1
• HES1
• HES3
• NOTCH1
• Occludin / OCLN

These markers can support research into neural stem cell identity, differentiation, Notch signaling, blood-brain barrier biology, and neural regeneration.

Explore Neural Stem Cell Marker Antibodies:

https://www.creative-diagnostics.com/neural-stem-cell-marker.htm

22/10/2026

Nipah virus (NiV) is a zoonotic henipavirus associated with severe neurological and respiratory disease, making reliable laboratory detection especially important for surveillance and research.

Our technical overview summarizes key approaches used in Nipah virus detection:

• Virus isolation and culture
• PCR and real-time molecular detection
• Genome sequencing
• ELISA-based serological testing
• Serum neutralization assays
• Pseudovirus-based neutralization approaches
• Immunohistochemistry
• Recombinant N, F, and G proteins for antibody detection

Each method offers different advantages depending on the research goal, sample type, biosafety requirements, and stage of infection.

Serological assays using recombinant NiV proteins can support antibody-response studies, while pseudovirus systems provide an alternative approach for evaluating neutralizing antibodies without directly working with infectious Nipah virus.

Explore the full overview:

https://www.creative-diagnostics.com/blog/index.php/nipah-virus-detection-method/

21/10/2026

Reliable antigen materials are essential across multiple stages of vaccine research—from conjugate vaccine design to the evaluation of vaccine-induced antibody responses.

Creative Diagnostics provides more than 40 native antigens from key infectious disease pathogens to support vaccine R&D.

Our portfolio includes:

• Tetanus toxoid (TT)
• Diphtheria toxoid (DT)
• Diphtheria CRM197
• Hib polyribosyl ribitol phosphate (PRP)
• Pneumococcal capsular polysaccharides (CPS)
• CPS-CRM197 conjugates for multiple pneumococcal serotypes
• Inactivated Enterovirus 71 and Coxsackievirus A16
• Inactivated Hepatitis A virus
• Inactivated Influenza A and B viruses
• Inactivated Rotavirus and Sabin Poliovirus
• Inactivated Zika virus

These materials can support conjugate vaccine development, antigen evaluation, immunogenicity research, and antibody-based assessment of vaccination responses.

Explore Native Antigens for Vaccine R&D:

https://www.creative-diagnostics.com/news-native-antigens-for-vaccine-rd-143.htm

20/10/2026

Epstein-Barr virus (EBV) serology relies on detecting antibody responses against different viral antigens produced during various stages of infection.

Creative Diagnostics provides recombinant EBV antigens designed to support IgG and IgM antibody testing and immunoassay development.

Key targets include:

• VCA p18
• VCA p23
• Early antigen p54
• Early antigen p138
• EBNA1 nuclear antigen
• IgG and IgM antibody detection
• ELISA and other serological immunoassays
• Differentiation of acute and past EBV infection

VCA, EA, and EBNA antibodies appear at different stages of the immune response, making antigen selection an important part of EBV serology assay design.

Explore EBV antigens for antibody testing:

https://www.creative-diagnostics.com/news-antigens-for-epstein-barr-virus-ebv-antibody-tests-146.htm

19/10/2026

MEDICA 2026 is less than one month away — and we’re looking forward to meeting you in Düsseldorf!

Creative Diagnostics will be exhibiting at MEDICA 2026, bringing together our expertise in IVD raw materials, immunoassay development, infectious disease research, and customized bioanalytical solutions.

Visit our team to explore:

• High-quality antibodies and antigens
• ELISA and lateral flow immunoassay solutions
• IVD raw materials for assay development
• Custom assay development and bioanalytical services
• Virology and antiviral research tools
• Vaccine development support
• Customized solutions for your specific R&D needs

More importantly, MEDICA is an opportunity to meet face-to-face.

Whether you are developing a new diagnostic assay, evaluating new raw material suppliers, looking for custom reagents, or exploring potential partnerships, we would be glad to discuss your project and learn more about your needs.

📍 Hall 3, Booth D19-4
📅 November 16–19, 2026
📌 Messe Düsseldorf, Germany

Planning to attend MEDICA?

Stop by our booth and meet the Creative Diagnostics team — or schedule a meeting with us in advance.

https://www.creative-diagnostics.com/medica-2026.htm

We look forward to seeing you in Düsseldorf!

16/10/2026

Reliable antigen selection is critical for developing sensitive HCV serology assays.

Creative Diagnostics provides matched recombinant HCV antigen pairs designed for double-antigen sandwich immunoassays and anti-HCV antibody detection.

Key features include:

• Multi-antigen combinations covering HCV Core, NS3, NS4, and NS5 regions
• Capture and detection antigen pairs
• Detection of HCV antibodies in serum
• Suitable for EIA, CLIA, and lateral flow applications
• ELISA validation using clinical serum samples
• HRP- and biotin-labeled antigen options
• Flexible antigen combinations for different assay formats

Using multiple immunoreactive HCV regions can help broaden antibody recognition and support the development of robust serological assays.

Explore matched antigen pairs for HCV serology test development:

https://www.creative-diagnostics.com/news-matched-antigen-pairs-for-hcv-serology-test-127.htm

15/10/2026

Foodborne pathogens can enter the food supply at multiple stages—from production and processing to transportation and preparation.

Reliable detection tools are therefore essential for identifying contamination and supporting food safety testing.

Creative Diagnostics provides a broad range of antigens and antibodies for foodborne pathogen detection assay development, covering:

• Salmonella
• Listeria monocytogenes
• Escherichia coli O157 and enterotoxins
• Campylobacter jejuni
• Shigella
• Vibrio cholerae
• Clostridium difficile toxins
• Staphylococcal enterotoxins
• Hepatitis A virus
• Giardia and Cryptosporidium

Many of these reagents are available as matched capture and detection antibodies for ELISA and lateral flow assay development.

From bacterial toxins to viral and parasitic targets, well-characterized reagents can help support the development of sensitive and reliable food safety testing solutions.

Explore foodborne pathogen detection materials:

https://www.creative-diagnostics.com/blog/index.php/food-source-pathogen-detection-tool-development-materials/

14/10/2026

Reliable antigen materials are essential for bacterial vaccine research and immunological assay development.

Inactivated bacterial antigens provide researchers with whole-cell materials that retain multiple native antigenic components while eliminating bacterial replication.

Creative Diagnostics offers a broad range of inactivated bacterial antigens to support vaccine research and assay development, including materials from clinically and scientifically important bacterial species.

Potential research applications include:

• Vaccine antigen screening
• Immunogenicity studies
• Antibody generation and characterization
• ELISA and other immunoassay development
• Positive controls and reference materials
• Host–pathogen interaction research
• Evaluation of bacterial immune responses

Whole-cell inactivated antigens can provide a broader antigenic profile than individual recombinant proteins, making them valuable tools for studies requiring complex bacterial antigen presentation.

Explore Inactivated Bacterial Antigens from Creative Diagnostics:

https://www.creative-diagnostics.com/news-inactivated-bacterial-antigens-for-vaccine-research-and-development-130.htm

13/10/2026

Antibody responses are central to antiviral immunity—but not every antibody-virus interaction is necessarily neutralizing.

Antibody-dependent enhancement (ADE) describes a mechanism in which virus-antibody complexes may interact with Fc receptors and increase viral entry into susceptible cells under certain experimental conditions.

Creative Diagnostics provides SARS-CoV-2 ADE assay services to support vaccine and antibody research.

Our assay workflow includes:

• Fc receptor-bearing effector cells such as Raji and K562 cells
• ACE2-expressing cells as positive system controls
• SARS-CoV-2 or pseudotyped SARS-CoV-2 systems
• Serial dilutions of test antibodies or serum
• Flow cytometry-based infection analysis
• Luciferase or GFP reporter-based readouts
• Untreated and non-enhancing controls
• 96-well assay formats for parallel testing

ADE assessment can complement neutralization studies when characterizing antibody activity across different concentrations and experimental conditions.

Explore the SARS-CoV-2 ADE Assay:

https://www.creative-diagnostics.com/sars-cov-2-ade-assay.htm

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