VTT Finland-Protein Production Team

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VTT Finland-Protein Production Team The VTT Protein Production Team offers world-class expertise in the development of protein production systems in microbes, plant cells and plants.

We provide custom recombinant protein production in our Expression service. We improve protein production hosts and carry out research to understand the molecular background and physiology of protein production. Our customers benefit by getting proteins produced efficiently or by advancing their own protein production technology. Partner with VTT to fulfill your protein production needs. The major global enzyme companies Genencor and AB Enzymes, have been our long-term research partners. In a protein expression commission for a client, we produced a recombinant enzyme at a level of 28 g/l. More than 30 years of experience in protein production technology in different host systems:

VTT is a leading research institute in the development of the filamentous fungus Trichoderma reesei as a production host. Our work in T. reesei has included native enzyme and recombinant protein production, the development of molecular and systems biology tools, the enhancement of productivity by strain engineering and the systems-wide investigation of the host physiology and optimisation of the fermentation process. We express recombinant proteins and improve their productivity also in plants and plant cells, yeasts and bacteria. We develop efficient high throughput screening procedures in different protein production hosts for enzyme discovery and engineering. Our strong competence and state of the art technology:

Our most important resources are our skilful and experienced personnel, excellent gene technology and systems biology tools and proprietary technology for protein expression and recovery and production system development. We can also provide technology transfer of protein production systems and technology to our customers. Our protein production research is well connected with VTT’s fermentation technology up to the pilot scale and with our enzyme development, protein engineering and metabolic modelling competences. We have worked mainly with industrial enzyme, chemical and therapeutic companies. Our protein production expertise can be also applied to liquid biofuel and platform chemicals production in biorefineries and in the food, feed and pulp and paper industries.

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