05/11/2026
How do immune cells know where to leave the bloodstream?🩸
When inflammation occurs, leukocytes cross the blood vessel wall to reach the affected tissue. But here's something fascinating: they don't necessarily cross just anywhere. Research suggests they use preferred exit sites, known as transmigration hotspots. But what makes these particular regions of the endothelium special?
Meet Jaap van Buul from Amsterdam UMC, the Netherlands, one of our keynote speakers at the Flow Meeting 2027! His research explores how endothelial heterogeneity influences where and how leukocytes cross the vessel wall. Using advanced lattice light-sheet microscopy, his team studies these dynamic interactions in real time🧬
At the Flow Meeting 2027, Jaap will present his keynote: “Where the Vessel Decides: Endothelial Heterogeneity, Inflammatory Hotspots, and Leukocyte Trafficking”
📍Explore the program and register: https://zurl.co/U4d78