Imperial Preterm Birth

Imperial Preterm Birth We are a team of clinical doctors, scientists & research midwives based at the Institute of Reproduc Globally there are 15 million preterm births a year.

It is the leading cause of death in children under the age of five and survivors are more at risk of cerebral palsy, blindness and respiratory problems. Currently, we do not have accurate ways to predict preterm birth, or subsequently find out why a mother has delivered early. Our group is investigating the mechanisms behind PTB to provide better diagnostic tools and treatments. https://www.imperial.nhs.uk/research/research-trials/reproductive-health-research-trials

Another great paper from the team describing the identification of sugars targeted by bacteria involved in preterm birth...
11/06/2025

Another great paper from the team describing the identification of sugars targeted by bacteria involved in preterm birth:

A study by Tajadura-Ortega et al. uses glycan microarrays to reveal how vaginal microbiota interacts with host glycans, offering insights into how glycan interactions influence bacterial colonization and competition.

Excited to share some new publications from the team.
11/06/2025

Excited to share some new publications from the team.

Here, the authors show that vaginal lactobacilli associated with optimal health interact selectively with a restricted subset of anti-inflammatory receptors through their Surface Layer Proteins, both in vitro and in cervicovaginal fluids, correlating with lower maternal inflammation.

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