10/20/2026
As biological questions grow more complex, cell culture models are expanding beyond
traditional 2D monolayers to 3D systems that better reflect human biology.
Models such as spheroids, organoids, and microphysiological systems (MPS) better
recapitulate in vivo conditions by enabling complex cell-cell and cell-matrix interactions, as
well as physiologically relevant nutrient and oxygen gradients, leading to more predictive
insights into drug performance.
Get our full guide on Developing Consistent and Reproducible 3D Spheroid Models:
Cell culture is evolving, and 3D applications are unlocking new possibilities. To make the transition easier, this application note offers clear guidance and practical tips for moving from 2D to 3D culture and generating uniform, consistent, and reproducible spheroids.